6l3y

X-ray diffraction
3.1Å resolution

Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-C

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184744 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine--tRNA ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 507 amino acids
Theoretical weight: 58.71 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IDJ8 (Residues: 77-583; Coverage: 87%)
Gene name: PF3D7_1350100
Sequence domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21212
Unit cell:
a: 299.841Å b: 52.831Å c: 70.44Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.225 0.28
Expression system: Escherichia coli