› 6ptv

X-ray diffraction
1.85Å resolution

Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin

Released:
DOI: 10.2210/pdb6ptv/pdb
PDB entry 6ptv coloured by chain, front view.
PDB entry 6ptv coloured by chain, side view.
PDB entry 6ptv coloured by chain, top view.
Source organisms:
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101798 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Beta sliding clamp Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 387 amino acids
Theoretical weight: 43.38 KDa
Source organism: Rickettsia rickettsii str. 'Sheila Smith'
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3AWV3 (Residues: 1-379; Coverage: 100%)
Gene name: A1G_03290
Sequence domains:
ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY Chains: X, Y
Molecule details ›
Chains: X, Y
Length: 11 amino acids
Theoretical weight: 1.12 KDa
Source organism: Streptomyces griseus
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MPD 2 x MPD
3 modified residues:
Ligand MVA 4 x MVA
Ligand MP8 4 x MP8
Ligand NZC 2 x NZC

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P1
Unit cell:
a: 77.21Å b: 82.79Å c: 82.86Å
α: 109.38° β: 89.94° γ: 106.53°
R-values:
R R work R free
0.169 0.169 0.206
Expression systems:
  • Escherichia coli
  • Not provided

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