› 6q5s

X-ray diffraction
1.89Å resolution

Crystal structure of a de novo designed antiparallel four-helix coiled coil apCC-Tet

Released:
DOI: 10.2210/pdb6q5s/pdb
PDB entry 6q5s coloured by chain, front view.
PDB entry 6q5s coloured by chain, side view.
PDB entry 6q5s coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Navigating the Structural Landscape of De Novo α-Helical Bundles.
Rhys GG, Wood CW, Beesley JL, Zaccai NR, Burton AJ, Brady RL, Thomson AR, Woolfson DN
J Am Chem Soc 141 8787-8797 (2019)
PMID: 31066556

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167301 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
apCC-Tet Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 32 amino acids
Theoretical weight: 3.23 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P41212
Unit cell:
a: 58.49Å b: 58.49Å c: 89.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.232
Expression system: Not provided

Quick links

Citations

2 review citations

Protein Design: From the Aspect of Water Solubility and Stability.
Qing et al. (2022)
1 more

2 mentions without citation

Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology.
Smith et al. (2023)
1 more