› 6ra5

X-ray diffraction
2.9Å resolution

Human tnik in complex with compound 9

Released:
DOI: 10.2210/pdb6ra5/pdb
PDB entry 6ra5 coloured by chain, front view.
PDB entry 6ra5 coloured by chain, side view.
PDB entry 6ra5 coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Read JA

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193844 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TRAF2 and NCK-interacting protein kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 306 amino acids
Theoretical weight: 35.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UKE5 (Residues: 11-314; Coverage: 22%)
Gene names: KIAA0551, TNIK
Sequence domains: Protein kinase domain

Ligands and Environments

2 bound ligands:
Ligand JWE 1 x JWE
Ligand MG 1 x MG
1 modified residue:
Ligand TPO 4 x TPO

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P32
Unit cell:
a: 53.793Å b: 53.793Å c: 253.363Å
α: 90° β: 90° γ: 120°
Expression system: Escherichia coli

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