› 6sds

X-ray diffraction
1.26Å resolution

Function and Biology Details

Reactions catalysed: 
H(2)CO(3) = CO(2) + H(2)O
Urea = cyanamide + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133681 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 2 Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 29.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00918 (Residues: 1-260; Coverage: 100%)
Gene name: CA2
Sequence domains: Eukaryotic-type carbonic anhydrase

Ligands and Environments

3 bound ligands:
Ligand ZN 1 x ZN
Ligand L8N 1 x L8N
Ligand DMS 1 x DMS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P21
Unit cell:
a: 42.224Å b: 41.241Å c: 71.946Å
α: 90° β: 104.11° γ: 90°
R-values:
R R work R free
0.147 0.146 0.174
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Organocatalytic asymmetric synthesis of P-stereogenic molecules.
Liu et al. (2023)
9 other articles

2 mentions without citation

From the psychosis prodrome to the first-episode of psychosis: No evidence of a cognitive decline.
Carrión et al. (2018)
1 more