6ti5 Citations

Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils.

Abstract

Recent structural studies show distinct morphologies for the fibrils of Aβ(1-42) and Aβ(1-40), which are believed not to co-fibrillize. We describe here a novel, structurally-uniform 1 : 1 mixed fibrillar species, which differs from both pure fibrils. It forms preferentially even when Aβ(1-42) : Aβ(1-40) peptides are mixed in a non-stoichiometric ratio.

Reviews - 6ti5 mentioned but not cited (1)

  1. Amyloid Cross-Seeding: Mechanism, Implication, and Inhibition. Subedi S, Sasidharan S, Nag N, Saudagar P, Tripathi T. Molecules 27 1776 (2022)

Articles - 6ti5 mentioned but not cited (7)



Reviews citing this publication (2)

  1. Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease. Martin W, Sheynkman G, Lightstone FC, Nussinov R, Cheng F. Curr Opin Struct Biol 72 103-113 (2022)
  2. Retinal Alterations Predict Early Prodromal Signs of Neurodegenerative Disease. Casciano F, Zauli E, Celeghini C, Caruso L, Gonelli A, Zauli G, Pignatelli A. Int J Mol Sci 25 1689 (2024)

Articles citing this publication (9)



Related citations provided by authors (1)