› 6yfy

Solid-state NMR

Solid-state NMR structure of the D-Arg4,L10-teixobactin - Lipid II complex in lipid bilayers.

Released:
DOI: 10.2210/pdb6yfy/pdb
PDB entry 6yfy coloured by chain, ensemble of 26 models, front view.
PDB entry 6yfy coloured by chain, ensemble of 26 models, side view.
PDB entry 6yfy coloured by chain, ensemble of 26 models, top view.
Source organisms:
Primary publication:
Mode of action of teixobactins in cellular membranes.
Shukla R, Medeiros-Silva J, Parmar A, Vermeulen BJA, Das S, Paioni AL, Jekhmane S, Lorent J, Bonvin AMJJ, Baldus M, Lelli M, Veldhuizen EJA, Breukink E, Singh I, Weingarth M
OpenAccess logo Nat Commun 11 2848 (2020)
PMID: 32503964

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-216012 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
D-Arg4,Leu10-Teixobactin Chains: A, B, E, F
Molecule details ›
Chains: A, B, E, F
Length: 11 amino acids
Theoretical weight: 1.25 KDa
Source organism: Eleftheria terrae
Expression system: Not provided
Lipid II Chains: C, D, G, H
Molecule details ›
Chains: C, D, G, H
Length: 5 amino acids
Theoretical weight: 490 Da
Source organism: Staphylococcus simulans

Ligands and Environments

Carbohydrate polymer : NEW Components: MUB, NAG
Carbohydrate polymer
2 bound ligands:
Ligand 2PO 8 x 2PO
Ligand P1W 12 x P1W
4 modified residues:
Ligand DAR 4 x DAR
Ligand DTH 4 x DTH
Ligand DGL 4 x DGL
Ligand DAL 8 x DAL

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 10%
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

11 review citations

A perspective on the PDB's impact on the field of glycobiology.
Prestegard JH. (2021)
10 more