› 6yje

X-ray diffraction
1.62Å resolution

Plasmoodium vivax phosphoglycerate kinase bound to nitrofuran inhibitor from PEG3350 and ammonium acetate at pH 5.5

Released:
DOI: 10.2210/pdb6yje/pdb
PDB entry 6yje coloured by chain, front view.
PDB entry 6yje coloured by chain, side view.
PDB entry 6yje coloured by chain, top view.
Source organism: Plasmodium vivax
Entry authors: Blaszczyk BK, Hyvonen M

Function and Biology Details

Reaction catalysed: 
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107672 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoglycerate kinase Chain: A
Molecule details ›
Chain: A
Length: 416 amino acids
Theoretical weight: 45.2 KDa
Source organism: Plasmodium vivax
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A5K6T9 (Residues: 2-416; Coverage: 100%)
Gene name: PVX_099535
Sequence domains: Phosphoglycerate kinase

Ligands and Environments

1 bound ligand:
Ligand OTQ 1 x OTQ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 41.962Å b: 81.246Å c: 124.331Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.196 0.232
Expression system: Escherichia coli BL21(DE3)

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