› 7b1a

X-ray diffraction
2.6Å resolution

Myosin-II-AA mutant motor domain

Released:
DOI: 10.2210/pdb7b1a/pdb
PDB entry 7b1a coloured by chain, front view.
PDB entry 7b1a coloured by chain, side view.
PDB entry 7b1a coloured by chain, top view.
Source organism: Dictyostelium discoideum
Primary publication:
Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and Pi Release.
Franz P, Ewert W, Preller M, Tsiavaliaris G
OpenAccess logo Int J Mol Sci 22 (2020)
PMID: 33374308

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Myosin-2 heavy chain Chain: A
Molecule details ›
Chain: A
Length: 788 amino acids
Theoretical weight: 89.95 KDa
Source organism: Dictyostelium discoideum
Expression system: Dictyostelium discoideum
UniProt:
  • Canonical: P08799 (Residues: 2-761; Coverage: 36%)
Gene names: DDB_G0286355, mhcA
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC, FRU
Carbohydrate polymer
4 bound ligands:
Ligand MG 1 x MG
Ligand EDO 3 x EDO
Ligand MLI 1 x MLI
Ligand AD9 1 x AD9
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup: C2221
Unit cell:
a: 89.764Å b: 146.47Å c: 154.845Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.209 0.263
Expression system: Dictyostelium discoideum

Quick links

Citations

1 review citation

Background and roles: myosin in autoimmune diseases.
Fu et al. (2023)
1 other article

3 mentions without citation

Interaction of Vanadium Complexes with Proteins: Revisiting the Reported Structures in the Protein Data Bank (PDB) since 2015.
Santos et al. (2023)
2 more