Function and Biology Details
Reaction catalysed:
Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172002 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonuclease SLFN12
Molecule details ›
Chains: A, C
Length: 583 amino acids
Theoretical weight: 67.38 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
Sequence domains:
Length: 583 amino acids
Theoretical weight: 67.38 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
- Canonical:
Q8IYM2 (Residues: 1-578; Coverage: 100%)
Sequence domains:
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
Molecule details ›
Chains: B, D
Length: 503 amino acids
Theoretical weight: 57.35 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
Sequence domains: 3'5'-cyclic nucleotide phosphodiesterase
Length: 503 amino acids
Theoretical weight: 57.35 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
- Canonical: Q14432 (Residues: 640-1141; Coverage: 44%)
Sequence domains: 3'5'-cyclic nucleotide phosphodiesterase
