7ut5

X-ray diffraction
1.4Å resolution

Acinetobacter baumannii dihydroorotate dehydrogenase bound with inhibitor DSM186

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-110480 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydroorotate dehydrogenase (quinone) Chains: A, B
Molecule details ›
Chains: A, B
Length: 354 amino acids
Theoretical weight: 38.3 KDa
Source organism: Acinetobacter baumannii
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: B7GZW7 (Residues: 1-334; Coverage: 100%)
Gene names: ABBFA_001187, pyrD
Sequence domains: Dihydroorotate dehydrogenase

Ligands and Environments


Cofactor: Ligand FMN 2 x FMN
3 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 45.53Å b: 89.77Å c: 84.417Å
α: 90° β: 90.036° γ: 90°
R-values:
R R work R free
0.166 0.166 0.174
Expression system: Escherichia coli BL21