› 8qns

X-ray diffraction
3.21Å resolution

Crystal structure of murine AIF bound to N-terminal domain of CHCHD4

Released:
DOI: 10.2210/pdb8qns/pdb
PDB entry 8qns coloured by chain, front view.
PDB entry 8qns coloured by chain, side view.
PDB entry 8qns coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Fagnani E, Milani M

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-275205 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Apoptosis-inducing factor 1, mitochondrial Chains: A, D, G, J
Molecule details ›
Chains: A, D, G, J
Length: 524 amino acids
Theoretical weight: 57.15 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Z0X1 (Residues: 101-612; Coverage: 84%)
Gene names: Aif, Aifm1, Pdcd8
Sequence domains:
Mitochondrial intermembrane space import and assembly protein 40 Chains: M, N, O, P
Molecule details ›
Chains: M, N, O, P
Length: 27 amino acids
Theoretical weight: 3.16 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q8VEA4 (Residues: 1-27; Coverage: 19%)
Gene names: Chchd4, Mia40

Ligands and Environments

2 bound ligands:
Ligand FAD 4 x FAD
Ligand NAD 4 x NAD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P212121
Unit cell:
a: 110.087Å b: 115.619Å c: 192.727Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.232 0.284
Expression systems:
  • Escherichia coli
  • Not provided

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