› 9enn

X-ray diffraction
1.8Å resolution

L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum in complex with N-epsilon-acetyl-L-lysine

Released:
DOI: 10.2210/pdb9enn/pdb
PDB entry 9enn coloured by chain, front view.
PDB entry 9enn coloured by chain, side view.
PDB entry 9enn coloured by chain, top view.
Source organism: Hebeloma cylindrosporum
Entry authors: Gilzer D, Koopmeiners S, Fischer von Mollard G, Niemann HH

Function and Biology Details

Reaction catalysed: 
An L-amino acid + H(2)O + O(2) = a 2-oxo carboxylate + NH(3) + H(2)O(2)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-250528 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amine oxidase domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 562 amino acids
Theoretical weight: 62.2 KDa
Source organism: Hebeloma cylindrosporum
Expression system: Escherichia coli
UniProt:
  • Canonical: S4S6Z0 (Residues: 54-615; Coverage: 92%)
Sequence domains: Flavin containing amine oxidoreductase

Ligands and Environments


Cofactor: Ligand FDA 4 x FDA
4 bound ligands:
Ligand ALY 4 x ALY
Ligand SO4 48 x SO4
Ligand PGR 10 x PGR
Ligand PGO 5 x PGO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P21
Unit cell:
a: 84.88Å b: 132.12Å c: 107.32Å
α: 90° β: 95.928° γ: 90°
R-values:
R R work R free
0.155 0.154 0.177
Expression system: Escherichia coli

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