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Cholesteryl ester transfer protein
CETP Enzyme: EC undefined This enzyme has known catalytic activity involved in reaction: cholesteryl (9Z,12Z)-octadecadienoate(in) = cholesteryl (9Z,12Z)-octadecadienoate(out) Disease Hyperalphalipoproteinemia 1: A condition characterized by high levels of high density lipoprotein (HDL) and increased HDL cholesterol levels.
Homo sapiens (Human)
P11597go to UniProt
Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:24293641, PubMed:3281933, PubMed:3600759). Regulates the reverse cholesterol transport, by ... [show more]go to UniProt
Representative structure for UniProt P11597
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PDB chain shown: 2obd A go to PDBe
UniProt residues 18 - 493
Coverage: 96%