Segment polarity protein dishevelled homolog DVL-1

Gene:

Dvl1

Organism:

Mus musculus (Mouse)

Synonyms:

Dvl

Uniprot:
Biological function:

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary ... [show more]go to UniProt


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PDB 3pz8 chain G (observed residues)
PDB 3pz8 chain G (observed residues)
PDB 3pz8 chain G (observed residues)
PDB 3pz8 chain G (observed residues)
PDB 2mx6 chain A (observed residues)
PDB 2mx6 chain A (observed residues)
PDB 1fsh chain A (observed residues)
PDB 1fsh chain A (observed residues)

PDB chain shown: 3pz8 G go to PDBe

UniProt residues 3 - 104

Coverage: 12%

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5
Structures

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1
Ligands

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0
Similarity


159
Publications

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