Ras-related protein Rab-7a

Organism:

Mus musculus (Mouse)

Synonyms:

Rab7

Uniprot:
Biological function:

Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins playing a key role in the regulation of endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not ... [show more]go to UniProt


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PDB 5z2m chain C (observed residues)
PDB 5z2m chain C (observed residues)
PDB 5z2m chain C (observed residues)
PDB 5z2m chain C (observed residues)

PDB chain shown: 5z2m C go to PDBe

UniProt residues 1 - 176

Coverage: 81%

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Structures

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60
Similarity

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21
Publications

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