Monocarboxylate transporter 1

Organism:

Mus musculus (Mouse)

Synonyms:

Mct1

Uniprot:
Biological function:

Bidirectional proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, acetate and the ketone bodies acetoacetate and beta-hydroxybutyrate, and thus contributes to the maintenance of intracellular pH (By similarity). The transport direction is determined by the proton motive force and the concentration gradient of the substrate monocarboxylate. MCT1 is a major ... [show more]go to UniProt


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PDB 7y1q chain A (observed residues)
PDB 7y1q chain A (observed residues)
PDB 7y1q chain A (observed residues)
PDB 7y1q chain A (observed residues)

PDB chain shown: 7y1q A go to PDBe

UniProt residues 1 - 493

Coverage: 76%

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14
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