- Display observed secondary structure variance per amino acid residue
Muscarinic toxin 1
Dendroaspis angusticeps (Eastern green mamba)
P81030go to UniProt
Shows a non-competitive interaction with adrenergic and muscarinic receptors. Binds to alpha-2b (ADRA2B) (IC(50)=2.3 nM), alpha-1a (ADRA1A), alpha-1b (ADRA1B), and alpha-2c (ADRA2C) adrenergic receptors. Reversibly binds to M1 (CHRM1) muscarinic acetylcholine receptors, probably by interacting with the orthosteric site (PubMed:12488533, PubMed:24793485, PubMed:7778123). Also reveals a slightly weaker effect at M3 (CHRM3) ... [show more]go to UniProt
Representative structure for UniProt P81030
Use the arrows or click on the blue segments at the bottom to navigate between representative chains from different PDB entries for different regions of the sequence.
Observed regions are darker shades, while unobserved regions are slightly transparent.
Note: There is a reported problem with Safari 15.1 that breaks the 3D viewer, Mol*. If Mol* is not displayed for you, please try a different browser, or update your Safari browser.
PDB chain shown: 4do8 B go to PDBe
UniProt residues 1 - 66
Coverage: 100%