Secretory phospholipase A2 receptor

Gene:

PLA2R1

Organism:

Homo sapiens (Human)

Synonyms:

CLEC13C

Uniprot:
Biological function:

Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phospholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on ... [show more]go to UniProt


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PDB 7qsr chain A (observed residues)
PDB 7qsr chain A (observed residues)
PDB 7qsr chain A (observed residues)
PDB 7qsr chain A (observed residues)

PDB chain shown: 7qsr A go to PDBe

UniProt residues 21 - 1397

Coverage: 91%

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