Cdc42-interacting protein 4

Gene:

TRIP10

Organism:

Homo sapiens (Human)

Synonyms:

CIP4, STOT, STP

Uniprot:
Biological function:

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the ... [show more]go to UniProt


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PDB 2efk chain A (observed residues)
PDB 2efk chain A (observed residues)
PDB 2efk chain A (observed residues)
PDB 2efk chain A (observed residues)
PDB 2ke4 chain A (observed residues)
PDB 2ke4 chain A (observed residues)
PDB 2ct4 chain A (observed residues)
PDB 2ct4 chain A (observed residues)

PDB chain shown: 2efk A go to PDBe

UniProt residues 10 - 303

Coverage: 45%

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3
Structures

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Ligands


1
Interactions

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