- Display observed secondary structure variance per amino acid residue
Probable E3 ubiquitin-protein ligase DTX2
Mus musculus (Mouse)
Q8R3P2go to UniProt
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, ... [show more]go to UniProt
Representative structure for UniProt Q8R3P2
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PDB chain shown: 1v87 A go to PDBe
UniProt residues 389 - 489
Coverage: 16%