Probable E3 ubiquitin-protein ligase DTX2

Organism:

Mus musculus (Mouse)

Uniprot:
Biological function:

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, ... [show more]go to UniProt


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Model 1 / 20
 
PDB 1v87 chain A (observed residues)
PDB 1v87 chain A (observed residues)

PDB chain shown: 1v87 A go to PDBe

UniProt residues 389 - 489

Coverage: 16%

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