- Display observed secondary structure variance per amino acid residue
Homeobox protein NANOG
NANOG
Homo sapiens (Human)
Q9H9S0go to UniProt
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a ... [show more]go to UniProt
Representative structure for UniProt Q9H9S0
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PDB chain shown: 2kt0 A go to PDBe
UniProt residues 75 - 157
Coverage: 27%