Entry status  (1)

REL

(15)

Experimental methods  (2)

Electron Microscopy

(12)

X-ray diffraction

(3)

Authors  (91)

BARRAUD P

(4)

Barraud P

(4)

Bhatta A

(4)

CATALA M

(4)

CHIRGADZE D

(4)

Catala M

(4)

Chirgadze DY

(4)

HARDWICK S

(4)

Hallberg BM

(4)

Hardwick SW

(4)

Hillen HS

(4)

Hällberg BM

(4)

LUISI B

(4)

Luisi BF

(4)

MEYNIER V

(4)

Meynier V

(4)

OERUM S

(4)

Oerum S

(4)

ROSKE J

(4)

Roske JJ

(4)

TISNE C

(4)

Tisne C

(4)

Tisné C

(4)

Valentin Gese G

(4)

Valentín Gesé G

(4)

Yue WW

(4)

Bohnsack KE

(3)

Ditter K

(3)

Kuhle B

(3)

Spanaus L

(3)

Yu RD

(3)

ARROWSMITH C

(1)

Abreo MA

(1)

Agree CS

(1)

Arancio O

(1)

Arrowsmith C

(1)

Aust RM

(1)

Caspersen C

(1)

Chaney M

(1)

Chen X

(1)

Cirilli M

(1)

Cramer P

(1)

DEBRECZENI J

(1)

Debreczeni J

(1)

Dienemann C

(1)

EDWARDS A

(1)

Edwards A

(1)

Gunn-Moore F

(1)

KAVANAGH KL

(1)

Kavanagh KL

(1)

Kissinger CR

(1)

Kuppusamy P

(1)

Li B

(1)

Lin C

(1)

Liu S

(1)

Lue LF

(1)

Lustbader JW

(1)

Margosiak S

(1)

Meng JJ

(1)

OPPERMANN U

(1)

Oppermann U

(1)

Pelletier LA

(1)

Pollak S

(1)

Rejto PA

(1)

SCHOLER K

(1)

SHAFQAT N

(1)

SUNDSTROM M

(1)

Scholer K

(1)

Shafqat N

(1)

Showalter RE

(1)

Stern D

(1)

Structural Genomics Consortium (SGC)

(1)

Sundstrom M

(1)

Takuma K

(1)

Tempczyk-Russell A

(1)

Thomson JA

(1)

Trinchese F

(1)

Vanderpool D

(1)

Villafranca JE

(1)

WEIGELT J

(1)

Walker DG

(1)

Wang N

(1)

Weigelt J

(1)

Wu H

(1)

Xu HW

(1)

YU W

(1)

Yan SS

(1)

ZSCHOCKE J

(1)

Zewier ZL

(1)

Zschocke J

(1)

von Delft F

(1)

Homo / hetero assembly  (2)

hetero

(12)

homo

(3)

Assembly composition  (2)

RNA/protein complex

(12)

protein structure

(3)

Assembly polymer count  (3)

heptamer

(10)

tetramer

(3)

hexamer

(2)

Resolution distribution

1.0 - 1.5

(1)

1.5 - 2

(2)

2.0 - 2.5

(1)

2.5 - 3

(7)

3.0 - 3.5

(4)

Release year distribution

2000 - 2005

(2)

2005 - 2010

(1)

2020 - 2025

(12)

2025 - 2030

(3)

Journal  (6)

EMBO J

(4)

Nat Commun

(4)

Nat Struct Mol Biol

(4)

J Mol Biol

(1)

Science

(1)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(15)

Organism name  (1)

Homo sapiens

(15)

Molecule name  (15)

17-beta-estradiol 17-dehydrogenase

(15)

2-methyl-3-hydroxybutyryl-CoA dehydrogenase

(15)

3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))

(15)

3-hydroxy-2-methylbutyryl-CoA dehydrogenase

(15)

3-hydroxyacyl-CoA dehydrogenase type II

(15)

3-hydroxyacyl-CoA dehydrogenase type-2

(15)

3alpha(or 20beta)-hydroxysteroid dehydrogenase

(15)

7-alpha-hydroxysteroid dehydrogenase

(15)

Endoplasmic reticulum-associated amyloid beta-peptide-binding protein

(15)

MHBD

(15)

Mitochondrial RNase P protein 2

(15)

Mitochondrial ribonuclease P protein 2

(15)

Short chain dehydrogenase/reductase family 5C member 1

(15)

Short-chain type dehydrogenase/reductase XH98G2

(15)

Type II HADH

(15)

Molecule type  (1)

Protein

(15)

Gene names  (7)

ERAB

(15)

HADH2

(15)

HSD17B10

(15)

MRPP2

(15)

SCHAD

(15)

SDR5C1

(15)

XH98G2

(15)

Interacting Molecules  (15)

tRNA methyltransferase 10 homolog C

(12)

Zinc phosphodiesterase ELAC protein 2

(7)

Mitochondrial ribonuclease P catalytic subunit

(2)

mt-tRNA-His-CCA

(2)

CCA tRNA nucleotidyltransferase 1, mitochondrial

(1)

Human mitochondria tRNA-Tyr precursor with 3' trailer

(1)

Human mitochondrial tRNA-Gln precursor with 3' trailer RNA

(1)

Human mitochondrial tRNA-Tyr precursor with 3' trailer

(1)

Mitochondrial Precursor tRNA-His(0,Ser)

(1)

Mitochondrial Precursor tRNA-His(5,Ser)

(1)

Mitochondrial Precursor tRNA-Ile(0,0)

(1)

Mitochondrial Precursor tRNA-Ile(5,4)

(1)

Mitochondrial Precursor tRNA-Tyr

(1)

mt-tRNA-His

(1)

tRNA-His-tRNA-Ser

(1)

Interacting ligands  (5)

NAD : NICOTINAMIDE-ADENINE-DINUCLEOTIDE

(7)

CL : CHLORIDE ION

(1)

GOL : GLYCEROL

(1)

NA : SODIUM ION

(1)

TDT : 1-AZEPAN-1-YL-2-PHENYL-2-(4-THIOXO-1,4-DIHYDRO-PYRAZOLO[3,4-D]PYRIMIDIN-5-YL)ETHANONE ADDUCT

(1)

EC number / name  (6)

1.1.1.159 : 7-alpha-hydroxysteroid dehydrogenase

(15)

1.1.1.178 : 3-hydroxy-2-methylbutyryl-CoA dehydrogenase

(15)

1.1.1.239 : 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))

(15)

1.1.1.35 : 3-hydroxyacyl-CoA dehydrogenase

(15)

1.1.1.53 : 3-alpha(or 20-beta)-hydroxysteroid dehydrogenase

(15)

1.1.1.62 : 17-beta-estradiol 17-dehydrogenase

(15)

Biological function  (15)

17-beta-hydroxysteroid dehydrogenase (NAD+) activity

(15)

3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity

(15)

3-hydroxyacyl-CoA dehydrogenase activity

(15)

RNA binding

(15)

androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity

(15)

chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity

(15)

cholate 7-alpha-dehydrogenase (NAD+) activity

(15)

estradiol 17-beta-dehydrogenase [NAD(P)+] activity

(15)

isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity

(15)

oxidoreductase activity

(15)

protein binding

(15)

tRNA binding

(15)

testosterone dehydrogenase (NAD+) activity

(15)

testosterone dehydrogenase [NAD(P)+] activity

(15)

ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity

(15)

Biological process  (16)

C21-steroid hormone metabolic process

(15)

androgen metabolic process

(15)

bile acid biosynthetic process

(15)

brexanolone metabolic process

(15)

estrogen metabolic process

(15)

fatty acid beta-oxidation

(15)

fatty acid metabolic process

(15)

isoleucine catabolic process

(15)

lipid metabolic process

(15)

mitochondrial tRNA 3'-end processing

(15)

mitochondrial tRNA 5'-end processing

(15)

mitochondrial tRNA methylation

(15)

mitochondrion organization

(15)

protein homotetramerization

(15)

steroid metabolic process

(15)

tRNA processing

(15)

Biological cell component  (7)

cytoplasm

(15)

mitochondrial matrix

(15)

mitochondrial nucleoid

(15)

mitochondrial ribonuclease P complex

(15)

mitochondrion

(15)

plasma membrane

(15)

tRNA methyltransferase complex

(15)

Compound cofactor class  (1)

Nicotinamide-adenine dinucleotide

(7)

SCOP fold  (1)

NAD(P)-binding Rossmann-fold domains

(3)

SCOP family  (1)

Tyrosine-dependent oxidoreductases

(3)

CATH class  (1)

Alpha Beta

(3)

CATH topology  (1)

Rossmann fold

(3)

Pfam accession / name  (1)

PF00106 : adh_short

(15)

Diffraction protocol  (1)

Single wavelength

(3)

Diffraction radiation source type  (2)

Synchrotron

(2)

Rotating anode

(1)

Diffraction source  (3)

APS BEAMLINE 32-ID

(1)

RIGAKU RU200

(1)

SLS BEAMLINE X10SA

(1)

Synchrotron site  (2)

APS

(1)

SLS

(1)

Diffraction detector type  (2)

CCD

(1)

Image plate

(1)

Refinement software  (4)

CNS

(1)

PHENIX

(1)

REFMAC

(1)

SHELXL-97

(1)

EM microscope model  (2)

TFS KRIOS

(8)

FEI TITAN KRIOS

(4)

EM detector name  (2)

GATAN K3 (6k x 4k)

(8)

GATAN K3 BIOQUANTUM (6k x 4k)

(4)

Representative Structures

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