Entry status  (1)

REL

(7)

Experimental methods  (1)

X-ray diffraction

(7)

Authors  (31)

Mattevi A

(5)

Caroli J

(4)

Baron R

(1)

Bier D

(1)

Binda C

(1)

Choi S

(1)

Halazonetis TD

(1)

Hong HR

(1)

Hou Z

(1)

Karar J

(1)

Lee SJ

(1)

Liu Y

(1)

McCammon JA

(1)

Mccammon JA

(1)

Ottmann C

(1)

Park IY

(1)

Peng H

(1)

Prokop JW

(1)

Qin YS

(1)

Rauscher III FJ

(1)

Sekimoto T

(1)

Shin YS

(1)

Son SY

(1)

Song J

(1)

Tortorici M

(1)

Waxman S

(1)

White D

(1)

Won YH

(1)

Yamashita E

(1)

Yasuhara N

(1)

Yoneda Y

(1)

Homo / hetero assembly  (1)

hetero

(7)

Assembly composition  (1)

protein/protein complex

(7)

Assembly polymer count  (3)

trimer

(5)

dimer

(1)

tetramer

(1)

Resolution distribution

1.0 - 1.5

(1)

2.5 - 3

(6)

Release year distribution

2010 - 2015

(3)

2015 - 2020

(1)

2020 - 2025

(4)

Journal  (3)

To be published

(5)

Acta Crystallogr D Biol Crystallogr

(1)

Structure

(1)

Organism superkingdom  (1)

Eukaryota

(7)

Organism name  (1)

Homo sapiens

(7)

Molecule name  (3)

Protein sna

(7)

Protein snail homolog 1

(7)

Zinc finger protein SNAI1

(7)

Molecule type  (1)

Protein

(7)

Gene names  (2)

SNAH

(7)

SNAI1

(7)

Interacting Molecules  (4)

Lysine-specific histone demethylase 1A

(5)

REST corepressor 1

(5)

14-3-3 protein sigma

(1)

Importin subunit beta-1

(1)

Interacting ligands  (5)

FAD : FLAVIN-ADENINE DINUCLEOTIDE

(1)

SV9 : [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-5-[7,8-dimethyl-2,4-bis(oxidanylidene)-5-[3-[4-(3-phenylphenyl)phenyl]propanoyl]-1~{H}-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate

(1)

XB6 : [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-{5-[3-([1,1'-biphenyl]-4-yl)propanoyl]-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl}-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name)

(1)

Y0Z : [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[7,8-dimethyl-2,4-dioxo-5-{3-[3-(phenylcarbamoyl)phenyl]propanoyl}-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate

(1)

ZN : ZINC ION

(1)

Biological function  (11)

DNA binding

(1)

DNA-binding transcription repressor activity, RNA polymerase II-specific

(1)

E-box binding

(1)

RNA polymerase II cis-regulatory region sequence-specific DNA binding

(1)

RNA polymerase II transcription regulatory region sequence-specific DNA binding

(1)

kinase binding

(1)

metal ion binding

(1)

protein binding

(1)

sequence-specific DNA binding

(1)

sequence-specific double-stranded DNA binding

(1)

zinc ion binding

(1)

Biological process  (27)

Notch signaling pathway

(1)

aortic valve morphogenesis

(1)

canonical Wnt signaling pathway

(1)

cartilage morphogenesis

(1)

epithelial cell migration

(1)

epithelial to mesenchymal transition

(1)

epithelial to mesenchymal transition involved in endocardial cushion formation

(1)

hair follicle morphogenesis

(1)

heterochromatin organization

(1)

left/right pattern formation

(1)

mesoderm development

(1)

mesoderm formation

(1)

negative regulation of DNA damage response, signal transduction by p53 class mediator

(1)

negative regulation of DNA-templated transcription

(1)

negative regulation of cell differentiation involved in embryonic placenta development

(1)

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

(1)

negative regulation of transcription by RNA polymerase II

(1)

negative regulation of vitamin D biosynthetic process

(1)

osteoblast differentiation

(1)

positive regulation of DNA-templated transcription

(1)

positive regulation of cell migration

(1)

positive regulation of epithelial to mesenchymal transition

(1)

regulation of DNA-templated transcription

(1)

regulation of bicellular tight junction assembly

(1)

regulation of transcription by RNA polymerase II

(1)

roof of mouth development

(1)

trophoblast giant cell differentiation

(1)

Biological cell component  (7)

cytoplasm

(1)

cytosol

(1)

fibrillar center

(1)

intracellular membrane-bounded organelle

(1)

nucleoplasm

(1)

nucleus

(1)

pericentric heterochromatin

(1)

Pfam accession / name  (2)

PF00096 : zf-C2H2

(1)

PF13912 : zf-C2H2_6

(1)

Diffraction protocol  (2)

Single wavelength

(7)

MAD

(1)

Diffraction radiation source type  (1)

Synchrotron

(7)

Diffraction source  (5)

ESRF BEAMLINE ID30B

(4)

PAL/PLS BEAMLINE 6C1

(1)

SLS BEAMLINE X10SA

(1)

SOLEIL BEAMLINE PROXIMA 1

(1)

SPRING-8 BEAMLINE BL44XU

(1)

Synchrotron site  (5)

ESRF

(4)

PAL/PLS

(1)

SLS

(1)

SOLEIL

(1)

SPring-8

(1)

Diffraction detector type  (2)

Pixel

(5)

CCD

(2)

Refinement software  (2)

PHENIX

(5)

REFMAC

(2)

Representative Structures

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