Uniprot accession / id : P05412  OR   Uniprot accession / id : Q08DH1  OR   Uniprot accession / id : P05627  OR   Uniprot accession / id : Q52L79  OR   Uniprot accession / id : P17325  OR   Uniprot accession / id : P18870  OR   Uniprot accession / id : Q6NZT5  OR   Uniprot accession / id : P18289  OR   Uniprot accession / id : A7UU92
 
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Entry Information
Entry status  (1)
REL
(10)
 
Experimental methods  (2)
X-ray diffraction
(9)
Solution NMR
(1)
 
Authors  (45)
Harrison SC
(3)
Chen L
(2)
Glover JN
(2)
Glover JNM
(2)
Wang D
(2)
Ballone A
(1)
Baxter D
(1)
Blumenthal RM
(1)
Brady RL
(1)
Brouwer P
(1)
Cheng X
(1)
Fairlie DP
(1)
Godfrey DI
(1)
Hill TA
(1)
Hogan PG
(1)
Hong S
(1)
Horton JR
(1)
Junius FK
(1)
Kim Y
(1)
King GF
(1)
Kok WM
(1)
Lameris R
(1)
Lau RA
(1)
Lutje Hulsik D
(1)
Maniatis T
(1)
Mason JM
(1)
Nilges M
(1)
O'Donoghue SI
(1)
Ottmann C
(1)
Panne D
(1)
Perry SR
(1)
Podust LM
(1)
Rao A
(1)
Rossjohn J
(1)
Shahine A
(1)
Speck SH
(1)
Stroud JC
(1)
Veth M
(1)
Weiss AS
(1)
Westerman B
(1)
Zaccai NR
(1)
Zhang X
(1)
Zweipfenning FPA
(1)
de Gruijl TD
(1)
van der Vliet HJ
(1)
 
Homo / hetero assembly  (2)
hetero
(9)
homo
(1)
 
Assembly composition  (3)
DNA/protein complex
(6)
protein/protein complex
(3)
protein structure
(1)
 
Assembly polymer count  (4)
tetramer
(4)
dimer
(2)
hexamer
(2)
pentamer
(2)
 
Resolution distribution
1.0 - 1.5
(1)
1.5 - 2
(2)
2.0 - 2.5
(2)
2.5 - 3
(2)
3.0 - 3.5
(2)
 
Release year distribution
1990 - 1995
(1)
1995 - 2000
(3)
2000 - 2005
(3)
2005 - 2010
(1)
2015 - 2020
(3)
2020 - 2025
(2)
 
Journal  (7)
To be published
(3)
Nature
(2)
Acta Crystallogr F Struct Biol Commun
(1)
EMBO J
(1)
J Biol Chem
(1)
J Immunother Cancer
(1)
Nucleic Acids Res
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(9)
 
Organism name  (2)
Homo sapiens
(9)
synthetic construct
(1)
 
Molecule name  (9)
AP1
(10)
Activator protein 1
(10)
Proto-oncogene c-Jun
(10)
Transcription factor AP-1 subunit Jun
(10)
Transcription factor Jun
(10)
V-jun avian sarcoma virus 17 oncogene homolog
(10)
p39
(10)
Antigen-presenting glycoprotein CD1d
(1)
R3G1
(1)
 
Molecule type  (1)
Protein
(10)
 
Representative Structures
Representative Structures
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Entries 1 to 10 of 10
Entries 1 to 10 of 10
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Structure of cJun-FosW coiled coil complex.
Zaccai NR, Mason JM, Brady RL
To be published
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: JEF    GOL    JEF   
Assembly name: Transcription factor Jun (Preferred)   search this complex
PDBe complex ID: PDB-CPX-138657 (Preferred)   search this ID
PDBe-KB: P05412   
X-ray diffraction
1.99Å resolution
Released: 7 Jun 2017
Model geometry
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5fv8
5fv8
5fv8
Human c-Jun DNA binding domain homodimer in complex with methylated DNA
Hong S, Horton JR, Cheng X
Nucleic Acids Res (2017) [PMID: 28158710  ]
Assembly composition: DNA/protein complex
Modified residues: 5CM    5CM   
Assembly name: bZIP transcription factor complex, JUN-JUN and DNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-119128 (Preferred)   search this ID
PDBe-KB: P05412   
X-ray diffraction
1.89Å resolution
Released: 1 Mar 2017
Model geometry
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5t01
5t01
5t01
14-3-3 Sigma in complex with phosphorylated c-Jun peptide
Ballone A, Lau RA, Zweipfenning FPA, Ottmann C
Acta Crystallogr F Struct Biol Commun (2020) [PMID: 33006579  ]
Assembly composition: protein/protein complex
Bound ligands: CA    MG    CA    MG   
Modified residues: SEP    SEP   
Assembly name: bZIP transcription factor complex, JUN-JUN and 14-3-3 protein sigma (Preferred)   search this complex
PDBe complex ID: PDB-CPX-138659 (Preferred)   search this ID
PDBe-KB: P05412    P31947   
X-ray diffraction
1.499Å resolution
Released: 14 Oct 2020
Model geometry
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6y3v
6y3v
6y3v
Human CD1d presenting sphingomyelin C24:1 in complex with VHH nanobody 1D17
Shahine A, Rossjohn J
J Immunother Cancer (2023) [PMID: 38040419  ]
Source organisms: Lama glama  , Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: NAG    NAG   
PDBe complex ID: PDB-CPX-242272 (Preferred)   search this ID
PDBe-KB: P15813    P05412    P61769   
X-ray diffraction
2.33Å resolution
Released: 13 Dec 2023
Model geometry
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8sos
8sos
8sos
Structure Of The DNA Binding Domains Of IRF3, ATF-2 and Jun Bound To DNA
Panne D, Maniatis T, Harrison SC
EMBO J (2004) [PMID: 15510218  ]
Source organisms: Synthetic construct, Homo sapiens  
Assembly composition: DNA/protein complex
Assembly name: bZIP transcription factor complex, ATF2-JUN and Interferon regulatory factor 3 and DNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-114625 (Preferred)   search this ID
PDBe-KB: P05412    P15336    Q14653   
X-ray diffraction
3Å resolution
Released: 16 Nov 2004
Model geometry
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1t2k
1t2k
1t2k
TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES
Glover JNM, Harrison SC
Nature (1995) [PMID: 7816143  ]
Source organisms: Synthetic construct, Homo sapiens  
Assembly composition: DNA/protein complex
Assembly name: bZIP transcription factor complex, FOS-JUN and DNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-113820 (Preferred)   search this ID
PDBe-KB: P05412    P01100   
X-ray diffraction
3.05Å resolution
Released: 10 Jul 1995
Model geometry
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Data not deposited
1fos
1fos
1fos
STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA
Chen L, Glover JNM, Hogan PG, Rao A, Harrison SC
Nature (1998) [PMID: 9510247  ]
Source organisms: Synthetic construct, Homo sapiens  
Assembly composition: DNA/protein complex
Assembly name: AP-1 transcription factor complex FOS-JUN-NFATC2 and DNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-113378 (Preferred)   search this ID
PDBe-KB: P05412    P01100    Q13469   
X-ray diffraction
2.7Å resolution
Released: 27 May 1998
Model geometry
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1a02
1a02
1a02
Crystal Structure of the Jun/CRE Complex
Kim Y, Podust LM
To be published
Source organism: Homo sapiens  
Assembly composition: DNA/protein complex
Assembly name: bZIP transcription factor complex, JUN-JUN and DNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-114019 (Preferred)   search this ID
PDBe-KB: P05412   
X-ray diffraction
2.2Å resolution
Released: 3 Jun 2003
Model geometry
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Data not deposited
1jnm
1jnm
1jnm
NMR STUDY OF C-JUN HOMODIMER
Junius FK, O'Donoghue SI, Nilges M, King GF
J Biol Chem (1996) [PMID: 8662824  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Modified residues: ACE    ACE   
Assembly name: bZIP transcription factor complex, JUN-JUN (Preferred)   search this complex
PDBe complex ID: PDB-CPX-138658 (Preferred)   search this ID
PDBe-KB: P05412   
Solution NMR
Released: 20 Jun 1996
Model geometry
Fit model/data
Data not analysed
1jun
1jun
1jun
Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site
Wang D, Stroud JC, Chen L
To be published
Source organisms: Synthetic construct, Homo sapiens  
Assembly composition: DNA/protein complex
Assembly name: AP-1 transcription factor complex FOS-JUN-NFATC2 and DNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-114582 (Preferred)   search this ID
PDBe-KB: P05412    P01100    Q13469   
X-ray diffraction
3.1Å resolution
Released: 14 Jun 2005
Model geometry
Fit model/data
1s9k
1s9k
1s9k
Entries 1 to 10 of 10
Entries 1 to 10 of 10