Uniprot accession / id : P06340  OR   Uniprot accession / id : F6WU08
 
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Entry Information
Entry status  (1)
REL
(1)
 
Experimental methods  (1)
X-ray diffraction
(1)
 
Authors  (7)
Guce AI
(1)
Jiang W
(1)
Mellins ED
(1)
Mortimer SE
(1)
Painter CA
(1)
Stern LJ
(1)
Yoon T
(1)
 
Homo / hetero assembly  (1)
hetero
(1)
 
Assembly composition  (1)
protein/protein complex
(1)
 
Assembly polymer count  (1)
tetramer
(1)
 
Resolution distribution
3.0 - 3.5
(1)
 
Release year distribution
2010 - 2015
(1)
 
Journal  (1)
Nat Struct Mol Biol
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(1)
 
Organism name  (1)
Homo sapiens
(1)
 
Molecule name  (4)
HLA class II histocompatibility antigen, DO alpha chain
(1)
MHC DN-alpha
(1)
MHC DZ alpha
(1)
MHC class II antigen DOA
(1)
 
Molecule type  (1)
Protein
(1)
 
Gene names  (3)
HLA-DNA
(1)
HLA-DOA
(1)
HLA-DZA
(1)
 
Interacting Molecules  (3)
HLA class II histocompatibility antigen, DM beta chain
(1)
HLA class II histocompatibility antigen, DO beta chain
(1)
Ig-like domain-containing protein
(1)
 
Interacting ligands  (2)
GOL : GLYCEROL
(1)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(1)
 
Function and Biology
Biological process  (2)
antigen processing and presentation
(1)
immune response
(1)
 
Biological cell component  (2)
MHC class II protein complex
(1)
membrane
(1)
 
Sequence and Structure classification
CATH class  (2)
Alpha Beta
(1)
Mainly Beta
(1)
 
CATH topology  (2)
Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1
(1)
Immunoglobulin-like
(1)
 
Pfam accession / name  (2)
PF00993 : MHC_II_alpha
(1)
PF07654 : C1-set
(1)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(1)
 
Diffraction radiation source type  (1)
Synchrotron
(1)
 
Representative Structures
Representative Structures
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HLA-DO in complex with HLA-DM
Guce AI, Mortimer SE, Stern LJ
Nat Struct Mol Biol (2013) [PMID: 23222639  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: ACT    GOL    NAG    NAG    ACT    PGE    PGE   
PDBe complex ID: PDB-CPX-139003 (Preferred)   search this ID
PDBe-KB: P06340    P28068    Q6ICR9    P13765   
X-ray diffraction
3.2Å resolution
Released: 26 Dec 2012
Model geometry
Fit model/data
4i0p
4i0p
4i0p
Entries 1 to 1 of 1
Entries 1 to 1 of 1