Uniprot accession / id : P20333  OR   Uniprot accession / id : Q3MHI9  OR   Uniprot accession / id : Q545P4  OR   Uniprot accession / id : P25119  OR   Uniprot accession / id : Q80WY6  OR   Uniprot accession / id : Q5ZL08  OR   Uniprot accession / id : A3KP87
 
Filter by :
Entry Information
Entry status  (1)
REL
(4)
 
Experimental methods  (2)
X-ray diffraction
(3)
Electron Microscopy
(1)
 
Authors  (41)
Ahn G
(1)
Akiba H
(1)
Baker D
(1)
Bera AK
(1)
Burkitt V
(1)
Chen W
(1)
Coventry B
(1)
Fujita J
(1)
Glogl M
(1)
Glögl M
(1)
Goreshnik I
(1)
Huang B
(1)
Ise T
(1)
Joyce E
(1)
Kamada H
(1)
Kang A
(1)
Kato T
(1)
Koepnick B
(1)
Krishnakumar A
(1)
Miyata T
(1)
Mukai Y
(1)
Nagata S
(1)
Nakagawa S
(1)
Nakamura T
(1)
Namba K
(1)
Nishiyama K
(1)
Ohno H
(1)
Park YC
(1)
Ragotte RJ
(1)
Sanchez MG
(1)
Tong L
(1)
Tsumoto K
(1)
Tsunoda S
(1)
Tsunoda SI
(1)
Tsutsumi Y
(1)
Villa AR
(1)
Wu H
(1)
Yamagata Y
(1)
Yang W
(1)
Yoshikawa M
(1)
Yoshioka Y
(1)
 
Homo / hetero assembly  (1)
hetero
(4)
 
Assembly composition  (1)
protein/protein complex
(4)
 
Assembly polymer count  (3)
pentamer
(2)
dimer
(1)
hexamer
(1)
 
Resolution distribution
1.5 - 2
(1)
2.0 - 2.5
(1)
2.5 - 3
(1)
3.5 - 4
(1)
 
Release year distribution
1995 - 2000
(1)
2005 - 2010
(1)
2010 - 2015
(1)
2020 - 2025
(2)
 
Journal  (4)
Commun Biol
(1)
Nature
(1)
Sci Signal
(1)
Science
(1)
 
Macromolecules
Organism superkingdom  (2)
Eukaryota
(4)
Bacteria
(1)
 
Organism name  (2)
Homo sapiens
(4)
Escherichia coli K-12
(1)
 
Molecule name  (17)
TBP-2
(4)
TBPII
(4)
TNF-R2
(4)
TNF-RII
(4)
TNFR-II
(4)
Tumor necrosis factor receptor 2
(4)
Tumor necrosis factor receptor superfamily member 1B
(4)
Tumor necrosis factor receptor superfamily member 1b, membrane form
(4)
Tumor necrosis factor receptor type II
(4)
Tumor necrosis factor-binding protein 2
(4)
p75
(4)
p80 TNF-alpha receptor
(4)
MBP
(1)
MMBP
(1)
Maltodextrin-binding protein
(1)
Maltose-binding protein
(1)
Maltose/maltodextrin-binding periplasmic protein
(1)
 
Molecule type  (1)
Protein
(4)
 
Gene names  (6)
TNFBR
(4)
TNFR2
(4)
TNFRSF1B
(4)
JW3994
(1)
b4034
(1)
malE
(1)
 
Interacting Molecules  (7)
TNF receptor-associated factor 2
(1)
TNFR2_mb1
(1)
TR109 heavy chain
(1)
TR109 light chain
(1)
TR92 heavy chain
(1)
TR92 light chain
(1)
Tumor necrosis factor, soluble form
(1)
 
Interacting ligands  (1)
CO : COBALT (II) ION
(1)
 
Function and Biology
Biological function  (4)
tumor necrosis factor receptor activity
(2)
carbohydrate transmembrane transporter activity
(1)
maltose binding
(1)
protein binding
(1)
 
Biological process  (9)
inflammatory response
(2)
DNA damage response
(1)
carbohydrate transmembrane transport
(1)
carbohydrate transport
(1)
cell chemotaxis
(1)
detection of maltose stimulus
(1)
maltodextrin transmembrane transport
(1)
maltose transport
(1)
transmembrane transport
(1)
 
Biological cell component  (6)
ATP-binding cassette (ABC) transporter complex
(1)
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
(1)
maltose transport complex
(1)
membrane
(1)
outer membrane-bounded periplasmic space
(1)
periplasmic space
(1)
 
Representative Structures
Representative Structures
100%
95%
90%
70%
50%
40%
30%
Entries 1 to 4 of 4
Entries 1 to 4 of 4
 Select all entries on this page
Crystal Structure of TNFR2 TNFR2_mb1 Complex
Bera AK, Glogl M, Baker D
Science (2024) [PMID: 39636970  ]
Assembly composition: protein/protein complex
Assembly name: Tumor necrosis factor-binding protein 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-281553 (Preferred)   search this ID
PDBe-KB: P20333   
X-ray diffraction
1.96Å resolution
Released: 4 Dec 2024
Model geometry
Fit model/data
9cu8
9cu8
9cu8
Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2
Akiba H, Fujita J, Ise T, Nishiyama K, Miyata T, Kato T, Namba K, Ohno H, Kamada H, Nagata S, Tsumoto K
Commun Biol (2023) [PMID: 37758868  ]
Assembly composition: protein/protein complex
Assembly name: Maltose/maltodextrin-binding periplasmic protein, Tumor necrosis factor-binding protein 2 and IG-heavy chain and IG-light kappa chain and IG-heavy cha... (Preferred)
show full assembly name   search this complex
PDBe complex ID: PDB-CPX-279598 (Preferred)   search this ID
PDBe-KB: P0AEX9    P20333   
Electron Microscopy
3.63Å resolution
Released: 4 Oct 2023
Model geometry
Fit model/data
Data not analysed
8hlb
8hlb
8hlb
Crystal structure of TNF-TNFR2 complex
Mukai Y, Nakamura T, Yamagata Y, Tsutsumi Y
Sci Signal (2010) [PMID: 21081755  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: CO    CO   
Assembly name: Soluble tumor necrosis factor complex and Tumor necrosis factor-binding protein 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-134287 (Preferred)   search this ID
PDBe-KB: P20333    P01375   
X-ray diffraction
3Å resolution
Released: 17 Nov 2010
Model geometry
Fit model/data
3alq
3alq
3alq
STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A PEPTIDE FROM TNF-R2
Park YC, Burkitt V, Villa AR, Tong L, Wu H
Nature (1999) [PMID: 10206649  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: Tumor necrosis factor-binding protein 2 and TNF receptor-associated factor 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-148932 (Preferred)   search this ID
PDBe-KB: P20333    Q12933   
X-ray diffraction
2.3Å resolution
Released: 12 Apr 1999
Model geometry
Fit model/data
Data not deposited
1ca9
1ca9
1ca9
Entries 1 to 4 of 4
Entries 1 to 4 of 4