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Entry status
(1)
Experimental methods
(2)
X-ray diffraction
(3)
Electron Microscopy
(1)
Authors
(41)
Ahn G
(1)
Akiba H
(1)
Baker D
(1)
Bera AK
(1)
Burkitt V
(1)
Chen W
(1)
Coventry B
(1)
Fujita J
(1)
Glogl M
(1)
Glögl M
(1)
Goreshnik I
(1)
Huang B
(1)
Ise T
(1)
Joyce E
(1)
Kamada H
(1)
Kang A
(1)
Kato T
(1)
Koepnick B
(1)
Krishnakumar A
(1)
Miyata T
(1)
Mukai Y
(1)
Nagata S
(1)
Nakagawa S
(1)
Nakamura T
(1)
Namba K
(1)
Nishiyama K
(1)
Ohno H
(1)
Park YC
(1)
Ragotte RJ
(1)
Sanchez MG
(1)
Tong L
(1)
Tsumoto K
(1)
Tsunoda S
(1)
Tsunoda SI
(1)
Tsutsumi Y
(1)
Villa AR
(1)
Wu H
(1)
Yamagata Y
(1)
Yang W
(1)
Yoshikawa M
(1)
Yoshioka Y
(1)
Homo / hetero assembly
(1)
hetero
(4)
Assembly composition
(1)
protein/protein complex
(4)
Assembly polymer count
(3)
pentamer
(2)
dimer
(1)
hexamer
(1)
Resolution distribution
1.5 - 2
(1)
2.0 - 2.5
(1)
2.5 - 3
(1)
3.5 - 4
(1)
Release year distribution
1995 - 2000
(1)
2005 - 2010
(1)
2010 - 2015
(1)
2020 - 2025
(2)
Journal
(4)
Commun Biol
(1)
Nature
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Macromolecules
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Eukaryota
(4)
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(1)
Organism name
(2)
Homo sapiens
(4)
Escherichia coli K-12
(1)
Molecule name
(17)
TBP-2
(4)
TBPII
(4)
TNF-R2
(4)
TNF-RII
(4)
TNFR-II
(4)
Tumor necrosis factor receptor 2
(4)
Tumor necrosis factor receptor superfamily member 1B
(4)
Tumor necrosis factor receptor superfamily member 1b, membrane form
(4)
Tumor necrosis factor receptor type II
(4)
Tumor necrosis factor-binding protein 2
(4)
p75
(4)
p80 TNF-alpha receptor
(4)
MBP
(1)
MMBP
(1)
Maltodextrin-binding protein
(1)
Maltose-binding protein
(1)
Maltose/maltodextrin-binding periplasmic protein
(1)
Molecule type
(1)
Protein
(4)
Gene names
(6)
TNFBR
(4)
TNFR2
(4)
TNFRSF1B
(4)
JW3994
(1)
b4034
(1)
malE
(1)
Interacting Molecules
(7)
TNF receptor-associated factor 2
(1)
TNFR2_mb1
(1)
TR109 heavy chain
(1)
TR109 light chain
(1)
TR92 heavy chain
(1)
TR92 light chain
(1)
Tumor necrosis factor, soluble form
(1)
Interacting ligands
(1)
CO : COBALT (II) ION
(1)
Function and Biology
Biological function
(4)
tumor necrosis factor receptor activity
(2)
carbohydrate transmembrane transporter activity
(1)
maltose binding
(1)
protein binding
(1)
Biological process
(9)
inflammatory response
(2)
DNA damage response
(1)
carbohydrate transmembrane transport
(1)
carbohydrate transport
(1)
cell chemotaxis
(1)
detection of maltose stimulus
(1)
maltodextrin transmembrane transport
(1)
maltose transport
(1)
transmembrane transport
(1)
Biological cell component
(6)
ATP-binding cassette (ABC) transporter complex
(1)
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
(1)
maltose transport complex
(1)
membrane
(1)
outer membrane-bounded periplasmic space
(1)
periplasmic space
(1)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
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Entries 1 to 4 of 4
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Crystal Structure of TNFR2 TNFR2_mb1 Complex
Bera AK, Glogl M, Baker D
Science
(2024)
[PMID: 39636970 ]
Source organisms: synthetic construct , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Tumor necrosis factor-binding protein 2
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-281553 (Preferred)
search this ID

Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2
Akiba H, Fujita J, Ise T, Nishiyama K, Miyata T, Kato T, Namba K, Ohno H, Kamada H, Nagata S, Tsumoto K
Commun Biol
(2023)
[PMID: 37758868 ]
Source organisms: Escherichia coli K-12 , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Maltose/maltodextrin-binding periplasmic protein, Tumor necrosis factor-binding protein 2 and IG-heavy chain and IG-light kappa chain and IG-heavy cha...
(Preferred)
show full assembly name search this complex
show full assembly name search this complex
PDBe complex ID:
PDB-CPX-279598 (Preferred)
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Crystal structure of TNF-TNFR2 complex
Mukai Y, Nakamura T, Yamagata Y, Tsutsumi Y
Sci Signal
(2010)
[PMID: 21081755 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Soluble tumor necrosis factor complex and Tumor necrosis factor-binding protein 2
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-134287 (Preferred)
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STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A PEPTIDE FROM TNF-R2
Park YC, Burkitt V, Villa AR, Tong L, Wu H
Nature
(1999)
[PMID: 10206649 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Tumor necrosis factor-binding protein 2 and TNF receptor-associated factor 2
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-148932 (Preferred)
search this ID
Entries 1 to 4 of 4