Entry status  (1)

REL

(4)

Experimental methods  (1)

X-ray diffraction

(4)

Authors  (74)

Bernier L

(2)

Chen H

(2)

Cho-Schultz S

(2)

Chung L

(2)

Collins M

(2)

Costa Jones C

(2)

Cronin CN

(2)

Del Bel M

(2)

Edwards M

(2)

Elleraas J

(2)

Fang X

(2)

Fisher T

(2)

Gallego RA

(2)

He M

(2)

Hoffman J

(2)

Huo R

(2)

Jalaie M

(2)

Johnson E

(2)

Johnson TW

(2)

Kania RS

(2)

Kraus M

(2)

Lafontaine J

(2)

Le P

(2)

Liu T

(2)

Maestre M

(2)

Matthews J

(2)

McTigue M

(2)

Miller N

(2)

Mu Q

(2)

Nair SK

(2)

Qin X

(2)

Ren S

(2)

Richardson P

(2)

Rohner A

(2)

Sach N

(2)

Shao L

(2)

Smith G

(2)

Su R

(2)

Sun B

(2)

Timofeevski S

(2)

Tran P

(2)

Wang S

(2)

Wang W

(2)

Zhou R

(2)

Zhu J

(2)

Arrowsmith C

(1)

Bochkarev A

(1)

Cowan-Jacob SW

(1)

Dhe-Paganon S

(1)

Edwards A

(1)

Evenou JP

(1)

Finerty Jr PJ

(1)

Finerty PJ

(1)

Floersheim P

(1)

Gaul C

(1)

Littler DR

(1)

MacKenzie F

(1)

Matt A

(1)

Monovich L

(1)

Newman EM

(1)

Rummel G

(1)

Schuler W

(1)

She YM

(1)

Soldermann N

(1)

Stark W

(1)

Strauss A

(1)

Structural Genomics Consortium (SGC)

(1)

Sundstrom M

(1)

Vangrevelinghe E

(1)

Wagner J

(1)

Walker JR

(1)

Weigelt J

(1)

van Eis MJ

(1)

von Matt A

(1)

Homo / hetero assembly  (1)

homo

(4)

Assembly composition  (1)

protein structure

(4)

Assembly polymer count  (1)

monomer

(4)

Resolution distribution

1.5 - 2

(2)

2.0 - 2.5

(2)

Release year distribution

2005 - 2010

(1)

2010 - 2015

(1)

2020 - 2025

(2)

Journal  (3)

J Med Chem

(2)

Biochem Biophys Res Commun

(1)

Bioorg Med Chem Lett

(1)

Organism superkingdom  (1)

Eukaryota

(4)

Organism name  (1)

Homo sapiens

(4)

Molecule name  (3)

PKC-L

(4)

Protein kinase C eta type

(4)

nPKC-eta

(4)

Molecule type  (1)

Protein

(4)

Gene names  (3)

PKCL

(4)

PRKCH

(4)

PRKCL

(4)

Interacting ligands  (3)

07U : 2-methyl-N~1~-[3-(pyridin-4-yl)-2,6-naphthyridin-1-yl]propane-1,2-diamine

(1)

XXF : (3P)-3-[6-chloro-4-(9-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile

(1)

Y3I : (3P)-3-{4-[(3R,5S)-3-amino-5-methylpiperidin-1-yl]-6-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile

(1)

EC number / name  (1)

2.7.11.13 : Protein kinase C

(4)

Biological function  (4)

ATP binding

(3)

diacylglycerol-dependent serine/threonine kinase activity

(3)

protein kinase activity

(3)

protein serine/threonine kinase activity

(3)

Biological process  (1)

protein phosphorylation

(3)

CATH class  (3)

Alpha Beta

(1)

Mainly Alpha

(1)

Mainly Beta

(1)

CATH topology  (3)

Immunoglobulin-like

(1)

Phosphorylase Kinase; domain 1

(1)

Transferase(Phosphotransferase); domain 1

(1)

Pfam accession / name  (3)

PF00069 : Pkinase

(3)

PF00433 : Pkinase_C

(3)

PF00168 : C2

(1)

Diffraction protocol  (1)

Single wavelength

(4)

Diffraction radiation source type  (2)

Synchrotron

(3)

Rotating anode

(1)

Diffraction source  (4)

APS BEAMLINE 17-ID

(1)

APS BEAMLINE 21-ID-E

(1)

RIGAKU FR-E

(1)

SLS BEAMLINE X10SA

(1)

Synchrotron site  (2)

APS

(2)

SLS

(1)

Diffraction detector type  (3)

Pixel

(2)

CCD

(1)

Image plate

(1)

Refinement software  (2)

BUSTER

(2)

REFMAC

(2)

Representative Structures

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