Uniprot accession / id : P36552  OR   Uniprot accession / id : P36551  OR   Uniprot accession / id : H0YA22
 
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Entry Information
Entry status  (1)
REL
(1)
 
Experimental methods  (1)
X-ray diffraction
(1)
 
Authors  (9)
Bodnarova M
(1)
Bodnárová M
(1)
Demeler B
(1)
Flachsova E
(1)
Flachsová E
(1)
Lee DS
(1)
Martasek P
(1)
Martásek P
(1)
Raman CS
(1)
 
Homo / hetero assembly  (1)
homo
(1)
 
Assembly composition  (1)
protein structure
(1)
 
Assembly polymer count  (1)
dimer
(1)
 
Resolution distribution
1.5 - 2
(1)
 
Release year distribution
2000 - 2005
(1)
2005 - 2010
(1)
 
Journal  (1)
Proc Natl Acad Sci U S A
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(1)
 
Organism name  (1)
Homo sapiens
(1)
 
Molecule name  (4)
COX
(1)
Coprogen oxidase
(1)
Coproporphyrinogenase
(1)
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
(1)
 
Molecule type  (1)
Protein
(1)
 
Gene names  (3)
CPO
(1)
CPOX
(1)
CPX
(1)
 
Interacting ligands  (1)
CIT : CITRIC ACID
(1)
 
Function and Biology
EC number / name  (1)
1.3.3.3 : Coproporphyrinogen oxidase
(1)
 
Biological function  (1)
coproporphyrinogen oxidase activity
(1)
 
Biological process  (1)
porphyrin-containing compound biosynthetic process
(1)
 
Sequence and Structure classification
CATH class  (1)
Alpha Beta
(1)
 
CATH topology  (1)
oxygen-dependent coproporphyrinogen oxidase
(1)
 
Pfam accession / name  (1)
PF01218 : Coprogen_oxidas
(1)
 
Experimental Information
Diffraction protocol  (1)
MAD
(1)
 
Diffraction radiation source type  (1)
Synchrotron
(1)
 
Diffraction source  (1)
ALS BEAMLINE 5.0.2
(1)
 
Synchrotron site  (1)
ALS
(1)
 
Diffraction detector type  (1)
CCD
(1)
 
Refinement software  (1)
REFMAC
(1)
 
Representative Structures
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The 1.58A Crystal Structure of Human Coproporphyrinogen Oxidase Reveals the Structural Basis of Hereditary Coproporphyria
Lee DS, Flachsova E, Bodnarova M, Demeler B, Martasek P, Raman CS
Proc Natl Acad Sci U S A (2005) [PMID: 16176984  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: CIT   
Assembly name: Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (Preferred)   search this complex
PDBe complex ID: PDB-CPX-153194 (Preferred)   search this ID
PDBe-KB: P36551   
X-ray diffraction
1.58Å resolution
Released: 2 Aug 2005
Model geometry
Fit model/data
2aex
2aex
2aex
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