Uniprot accession / id : P40967  OR   Uniprot accession / id : Q06154  OR   Uniprot accession / id : Q9CZB2  OR   Uniprot accession / id : Q98917  OR   Uniprot accession / id : Q1JQ71
 
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Entry Information
Entry status  (1)
REL
(19)
 
Experimental methods  (2)
X-ray diffraction
(13)
Electron Microscopy
(6)
 
Authors  (53)
Baker BM
(7)
Alonso JA
(5)
Ayres CM
(5)
Hellman LM
(5)
Oda T
(5)
Singh NK
(5)
Smith AR
(5)
Yanagisawa H
(5)
Attaf M
(4)
Bianchi V
(4)
Bulek A
(4)
Cole DK
(4)
Dolton G
(4)
Fuller A
(4)
Lloyd A
(4)
Rizkallah PJ
(4)
Sewell AK
(4)
Baxter TK
(2)
Borbulevych OY
(2)
Restifo NP
(2)
Yu Z
(2)
Achour A
(1)
Badia-Martinez D
(1)
Chen S
(1)
Davis SJ
(1)
Depontieu FR
(1)
English AM
(1)
Fernandes RA
(1)
Hummer G
(1)
Hunt DF
(1)
Kos F
(1)
Li Y
(1)
Mariuzza RA
(1)
McMiller TL
(1)
O'Brien-Ball C
(1)
Offringa R
(1)
Rosenberg SA
(1)
Santos AM
(1)
Sette A
(1)
Shabanowitz J
(1)
Sidney J
(1)
Sluijter M
(1)
Susac L
(1)
Sušac L
(1)
Tampe R
(1)
Tampé R
(1)
Thomas C
(1)
Topalian SL
(1)
Vuong MT
(1)
van Hall T
(1)
van Stipdonk MJ
(1)
von Bulow S
(1)
von Bülow S
(1)
 
Homo / hetero assembly  (2)
hetero
(14)
homo
(5)
 
Assembly composition  (2)
protein/protein complex
(14)
protein structure
(5)
 
Assembly polymer count  (4)
trimer
(7)
pentamer
(6)
octamer
(5)
undecamer
(1)
 
Resolution distribution
1.5 - 2
(10)
2.0 - 2.5
(5)
2.5 - 3
(3)
3.0 - 3.5
(1)
 
Release year distribution
2000 - 2005
(2)
2005 - 2010
(3)
2010 - 2015
(1)
2015 - 2020
(5)
2020 - 2025
(11)
 
Journal  (7)
To be published
(5)
J Biol Chem
(4)
Proc. Natl. Acad. Sci. U.S.A.
(4)
J Immunol
(3)
Cancer Res
(1)
Cell
(1)
Proc Natl Acad Sci U S A
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(16)
 
Organism name  (2)
Homo sapiens
(16)
synthetic construct
(3)
 
Molecule name  (17)
95 kDa melanocyte-specific secreted glycoprotein
(19)
M-alpha
(19)
M-beta
(19)
ME20-M
(19)
ME20-S
(19)
ME20M
(19)
ME20S
(19)
Melanocyte protein PMEL
(19)
Melanocyte protein Pmel 17
(19)
Melanocytes lineage-specific antigen GP100
(19)
Melanoma-associated ME20 antigen
(19)
P1
(19)
P100
(19)
P26
(19)
Premelanosome protein
(19)
Secreted melanoma-associated ME20 antigen
(19)
Silver locus protein homolog
(19)
 
Molecule type  (1)
Protein
(19)
 
Gene names  (4)
D12S53E
(19)
PMEL
(19)
PMEL17
(19)
SILV
(19)
 
Interacting Molecules  (20)
Beta-2-microglobulin
(13)
HLA class I histocompatibility antigen, A alpha chain
(7)
Ig-like domain-containing protein
(6)
T4H2 T cell receptor alpha chain
(3)
T4H2 T cell receptor beta chain
(3)
SILv44 T cell receptor alpha chain
(2)
SILv44 T cell receptor beta chain
(2)
Green fluorescent protein
(1)
H-2 class I histocompatibility antigen, D-B alpha chain
(1)
HLA class II histocompatibility antigen, DR alpha chain
(1)
HLA class II histocompatibility antigen, DRB1 beta chain
(1)
T cell receptor alpha chain constant
(1)
T cell receptor alpha variable 21
(1)
T cell receptor beta constant 2
(1)
T-cell receptor alpha chain
(1)
T-cell receptor beta chain
(1)
T-cell surface glycoprotein CD3 delta chain
(1)
T-cell surface glycoprotein CD3 epsilon chain
(1)
T-cell surface glycoprotein CD3 gamma chain
(1)
T-cell surface glycoprotein CD3 zeta chain
(1)
 
Interacting ligands  (2)
GOL : GLYCEROL
(3)
EDO : 1,2-ETHANEDIOL
(2)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(13)
 
Diffraction radiation source type  (1)
Synchrotron
(13)
 
Diffraction source  (7)
APS BEAMLINE 22-ID
(4)
APS BEAMLINE 19-BM
(2)
DIAMOND BEAMLINE I02
(2)
DIAMOND BEAMLINE I03
(2)
APS BEAMLINE 23-ID-D
(1)
ESRF BEAMLINE ID14-1
(1)
NSLS BEAMLINE X29A
(1)
 
Synchrotron site  (4)
APS
(7)
Diamond
(4)
ESRF
(1)
NSLS
(1)
 
Diffraction detector type  (2)
Pixel
(9)
CCD
(4)
 
Refinement software  (3)
REFMAC
(7)
PHENIX
(6)
CNS
(1)
 
EM microscope model  (2)
JEOL CRYO ARM 300
(5)
FEI TITAN KRIOS
(1)
 
EM detector name  (2)
GATAN K3 (6k x 4k)
(5)
GATAN K2 SUMMIT (4k x 4k)
(1)
 
Representative Structures
Representative Structures
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Entries 1 to 10 of 19
Entries 1 to 10 of 19
 Select all entries on this page
HLA Class I antigen
Rizkallah PJ, Bianchi V, Cole DK, Sewell AK
J Biol Chem (2016) [PMID: 26917722  ]
Assembly composition: protein/protein complex
Bound ligands: GOL    SO4    EDO   
PDBe complex ID: PDB-CPX-137690 (Preferred)   search this ID
PDBe-KB: P40967    P04439    P61769   
X-ray diffraction
2.12Å resolution
Released: 2 Mar 2016
Model geometry
Fit model/data
5eu4
5eu4
5eu4
HLA Class I antigen
Rizkallah PJ, Bianchi V, Cole DK, Sewell AK
J Biol Chem (2016) [PMID: 26917722  ]
Assembly composition: protein/protein complex
Bound ligands: GOL    SO4    EDO   
PDBe complex ID: PDB-CPX-137690 (Preferred)   search this ID
PDBe-KB: P40967    P04439    P61769   
X-ray diffraction
1.54Å resolution
Released: 2 Mar 2016
Model geometry
Fit model/data
5eu5
5eu5
5eu5
HLA Class I antigen
Rizkallah PJ, Bianchi V, Cole DK, Sewell AK
J Biol Chem (2016) [PMID: 26917722  ]
Assembly composition: protein/protein complex
Bound ligands: GOL    SO4    EDO   
PDBe complex ID: PDB-CPX-100944 (Preferred)   search this ID
PDBe-KB: P40967    A0A0B4J279    P04439    P01848    A0A592    P61769    (view 1 more)
X-ray diffraction
2.02Å resolution
Released: 2 Mar 2016
Model geometry
Fit model/data
5eu6
5eu6
5eu6
HLA Class I antigen
Rizkallah PJ, Bianchi V, Cole DK, Sewell AK
J Biol Chem (2016) [PMID: 26917722  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: GOL    EDO   
PDBe complex ID: PDB-CPX-137690 (Preferred)   search this ID
PDBe-KB: P40967    P04439    P61769   
X-ray diffraction
1.97Å resolution
Released: 2 Mar 2016
Model geometry
Fit model/data
5eu3
5eu3
5eu3
G175S PMEL CAF amyloid - in vitro polymerized
Oda T, Yanagisawa H
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: M-alpha (Preferred)   search this complex
PDBe complex ID: PDB-CPX-273697 (Preferred)   search this ID
PDBe-KB: P40967   
Electron Microscopy
1.79Å resolution
Released: 9 Oct 2024
Model geometry
Fit model/data
Data not analysed
9jsx
9jsx
9jsx
Wild-type PMEL CAF amyloid -in vitro polymerized
Oda T, Yanagisawa H
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: M-alpha (Preferred)   search this complex
PDBe complex ID: PDB-CPX-273697 (Preferred)   search this ID
PDBe-KB: P40967   
Electron Microscopy
1.94Å resolution
Released: 9 Oct 2024
Model geometry
Fit model/data
Data not analysed
9jsw
9jsw
9jsw
Wild-type native PMEL amyloid - polymorph 2
Oda T, Yanagisawa H
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: M-alpha (Preferred)   search this complex
PDBe complex ID: PDB-CPX-273697 (Preferred)   search this ID
PDBe-KB: P40967   
Electron Microscopy
1.79Å resolution
Released: 9 Oct 2024
Model geometry
Fit model/data
Data not analysed
9jsu
9jsu
9jsu
G175S mutant native PMEL amyloid
Oda T, Yanagisawa H
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: M-alpha (Preferred)   search this complex
PDBe complex ID: PDB-CPX-273697 (Preferred)   search this ID
PDBe-KB: P40967   
Electron Microscopy
1.79Å resolution
Released: 9 Oct 2024
Model geometry
Fit model/data
Data not analysed
9jsv
9jsv
9jsv
Wild-type native PMEL amyloid - polymorph 1
Oda T, Yanagisawa H
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: M-alpha (Preferred)   search this complex
PDBe complex ID: PDB-CPX-273697 (Preferred)   search this ID
PDBe-KB: P40967   
Electron Microscopy
1.79Å resolution
Released: 9 Oct 2024
Model geometry
Fit model/data
Data not analysed
9jst
9jst
9jst
T4H2 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV)
Smith AR, Baker BM
Proc. Natl. Acad. Sci. U.S.A. (2021)
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
PDBe complex ID: PDB-CPX-231547 (Preferred)   search this ID
PDBe-KB: P40967    A0A140T913    P61769   
X-ray diffraction
2.9Å resolution
Released: 20 Jan 2021
Model geometry
Data not analysed
Fit model/data
Data not analysed
6vm9
6vm9
6vm9
Entries 1 to 10 of 19
Entries 1 to 10 of 19