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Malinauskas T
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Mueller TD
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Siebold C
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Muller TD
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Bishop B
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Peer TV
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Ashe H
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Belnoue-Davis HL
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Duman R
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Eggington H
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El Omari K
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Griffiths SC
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Kotzsch A
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Leedham SJ
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Moore G
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Nickel J
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Rudolf AF
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Sebald W
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Woolley RE
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Kattamuri C
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Thompson TB
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Zorn AM
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Hellmann TV
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Henson F
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BMP-14
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Bone morphogenetic protein 14
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Cartilage-derived morphogenetic protein 1
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Growth/differentiation factor 5
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Cystine Knot Cytokines, subunit B
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PF00019 : TGF_beta
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(2)
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Representative Structures
Representative Structures
Entries
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Entries 1 to 10 of 15
Select all entries on this page
Crystal structure of the GDF-5:BMP receptor IB complex.
Kotzsch A, Mueller TD
EMBO J
(2009)
[PMID: 19229295 ]
Source organisms: Mus musculus , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Growth/differentiation factor 5 and Bone morphogenetic protein receptor type-1B
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-153254 (Preferred)
search this ID
Crystal structure of a TGF-beta ligand-receptor complex
Mueller TD, Nickel J, Sebald W
BMC Biol
(2015)
[PMID: 26385096 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Bone morphogenetic protein receptor type-1A and Growth/differentiation factor 5
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-153247 (Preferred)
search this ID
Crystal structure of human Twisted gastrulation protein homolog 1 (TWSG1) in complex with human Growth Differentiation Factor 5 (GDF5) and calcium, long-wavelength X-ray dataset (4010 eV)
Malinauskas T, Rudolf AF, Moore G, Eggington H, Belnoue-Davis H, El Omari K, Woolley RE, Griffiths SC, Duman R, Wagner A, Leedham SJ, Baldock C, Ashe H, Siebold C
Nat Commun
(2024)
[PMID: 38862520 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Growth/differentiation factor 5 and Twisted gastrulation protein homolog 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-273754 (Preferred)
search this ID
Crystal structure of human Twisted gastrulation protein homolog 1 (TWSG1) in complex with human Growth Differentiation factor 5 (GDF5) and calcium
Malinauskas T, Rudolf AF, Moore G, Eggington H, Belnoue-Davis H, El Omari K, Woolley RE, Griffiths SC, Duman R, Wagner A, Leedham SJ, Baldock C, Ashe H, Siebold C
Nat Commun
(2024)
[PMID: 38862520 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Growth/differentiation factor 5 and Twisted gastrulation protein homolog 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-273754 (Preferred)
search this ID
Crystal structure of human Twisted gastrulation protein homolog 1 (TWSG1) in complex with human Growth Differentiation factor 5 (GDF5) and calcium, long-wavelength X-ray dataset (4042 eV)
Malinauskas T, Rudolf AF, Moore G, Eggington H, Belnoue-Davis H, El Omari K, Woolley RE, Griffiths SC, Duman R, Wagner A, Leedham SJ, Baldock C, Ashe H, Siebold C
Nat Commun
(2024)
[PMID: 38862520 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Growth/differentiation factor 5 and Twisted gastrulation protein homolog 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-273754 (Preferred)
search this ID
BMP2/GDF5 heterodimer
Gipson GR, Nolan KT, Thompson TB
BMC Biol
(2023)
[PMID: 36726183 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Bound ligands:
GOL
Assembly name:
Growth/differentiation factor 5 and Bone morphogenetic protein 2
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-273194 (Preferred)
search this ID
Repulsive Guidance Molecule B (RGMB) in complex with Growth Differentiation Factor 5 (GDF5) (crystal form 2)
Malinauskas T, Peer TV, Bishop B, Muller TD, Siebold C
Proc Natl Acad Sci U S A
(2020)
[PMID: 32576689 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Growth/differentiation factor 5 and Repulsive guidance molecule B
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-154936 (Preferred)
search this ID
Repulsive Guidance Molecule C (RGMC, Hemojuvelin, HJV, HFE2) in complex with Growth Differentiation Factor 5 (GDF5)
Malinauskas T, Peer TV, Bishop B, Muller TD, Siebold C
Proc Natl Acad Sci U S A
(2020)
[PMID: 32576689 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Growth/differentiation factor 5 and Hemojuvelin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-154937 (Preferred)
search this ID
Repulsive Guidance Molecule B (RGMB) in complex with Growth Differentiation Factor 5 (GDF5) and Neogenin 1 (NEO1).
Malinauskas T, Peer TV, Bishop B, Muller TD, Siebold C
Proc Natl Acad Sci U S A
(2020)
[PMID: 32576689 ]
Source organisms: Mus musculus , Homo sapiens
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-216334 (Preferred)
search this ID
Repulsive Guidance Molecule B (RGMB) in complex with Growth Differentiation Factor 5 (GDF5) (crystal form 1)
Malinauskas T, Peer TV, Bishop B, Muller TD, Siebold C
Proc Natl Acad Sci U S A
(2020)
[PMID: 32576689 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Growth/differentiation factor 5 and Repulsive guidance molecule B
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-154936 (Preferred)
search this ID
Entries 1 to 10 of 15