Entry status  (1)

REL

(3)

Experimental methods  (1)

X-ray diffraction

(3)

Authors  (8)

Tesmer JJ

(3)

Boguth CA

(2)

Huang CC

(2)

Singh P

(2)

Tesmer JJG

(2)

Benovic JL

(1)

Lodowski DT

(1)

Tesmer VM

(1)

Homo / hetero assembly  (1)

homo

(3)

Assembly composition  (1)

protein structure

(3)

Assembly polymer count  (2)

monomer

(2)

dimer

(1)

Resolution distribution

2.5 - 3

(3)

Release year distribution

2005 - 2010

(3)

2010 - 2015

(2)

Journal  (2)

EMBO J

(2)

J Biol Chem

(1)

Organism superkingdom  (1)

Eukaryota

(3)

Organism name  (1)

Homo sapiens

(3)

Molecule name  (2)

G protein-coupled receptor kinase 6

(3)

G protein-coupled receptor kinase GRK6

(3)

Molecule type  (1)

Protein

(3)

Gene names  (2)

GPRK6

(3)

GRK6

(3)

Interacting ligands  (6)

BU3 : (R,R)-2,3-BUTANEDIOL

(2)

SO4 : SULFATE ION

(2)

AMP : ADENOSINE MONOPHOSPHATE

(1)

ANP : PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER

(1)

PO4 : PHOSPHATE ION

(1)

SGV : SANGIVAMYCIN

(1)

EC number / name  (1)

2.7.11.16 : G-protein-coupled receptor kinase

(3)

Biological function  (9)

ATP binding

(3)

G protein-coupled receptor kinase activity

(3)

beta-adrenergic receptor kinase activity

(3)

kinase activity

(3)

nucleotide binding

(3)

protein binding

(3)

protein kinase activity

(3)

protein serine/threonine kinase activity

(3)

transferase activity

(3)

Biological process  (6)

G protein-coupled receptor signaling pathway

(3)

Wnt signaling pathway

(3)

protein phosphorylation

(3)

regulation of G protein-coupled receptor signaling pathway

(3)

regulation of signal transduction

(3)

signal transduction

(3)

Biological cell component  (3)

cytoplasm

(3)

membrane

(3)

plasma membrane

(3)

CATH class  (3)

Alpha Beta

(3)

Mainly Alpha

(3)

Special

(1)

CATH topology  (5)

Phosphorylase Kinase; domain 1

(3)

Regulator of G-protein Signalling 4; domain 2

(3)

Transferase(Phosphotransferase); domain 1

(3)

Helix Hairpins

(1)

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

(1)

Pfam accession / name  (2)

PF00069 : Pkinase

(3)

PF00615 : RGS

(3)

Diffraction protocol  (1)

Single wavelength

(3)

Diffraction radiation source type  (1)

Synchrotron

(3)

Diffraction source  (2)

APS BEAMLINE 21-ID-G

(2)

ALS BEAMLINE 8.3.1

(1)

Synchrotron site  (2)

APS

(2)

ALS

(1)

Diffraction detector type  (1)

CCD

(3)

Refinement software  (1)

REFMAC

(3)

Representative Structures

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