Uniprot accession / id : P55075  OR   Uniprot accession / id : A1A515  OR   Uniprot accession / id : P37237  OR   Uniprot accession / id : Q80ZL6  OR   Uniprot accession / id : Q76LI5  OR   Uniprot accession / id : Q90722  OR   Uniprot accession / id : Q5PRC3
 
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Entry Information
Entry status  (1)
REL
(1)
 
Experimental methods  (1)
X-ray diffraction
(1)
 
Authors  (11)
Bromleigh C
(1)
Eliseenkova AV
(1)
Ibrahimi OA
(1)
Joyner AL
(1)
Lao Z
(1)
Li JY
(1)
Li JYH
(1)
Linhardt RJ
(1)
Mohammadi M
(1)
Olsen SK
(1)
Zhang F
(1)
 
Homo / hetero assembly  (1)
hetero
(1)
 
Assembly composition  (1)
protein/protein complex
(1)
 
Assembly polymer count  (1)
dimer
(1)
 
Resolution distribution
2.0 - 2.5
(1)
 
Release year distribution
2005 - 2010
(1)
 
Journal  (1)
Genes Dev
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(1)
 
Organism name  (1)
Homo sapiens
(1)
 
Molecule name  (6)
AIGF
(1)
Androgen-induced growth factor
(1)
FGF-8
(1)
Fibroblast growth factor 8
(1)
HBGF-8
(1)
Heparin-binding growth factor 8
(1)
 
Molecule type  (1)
Protein
(1)
 
Gene names  (2)
AIGF
(1)
FGF8
(1)
 
Interacting Molecules  (1)
Fibroblast growth factor receptor 2
(1)
 
Function and Biology
Biological function  (1)
growth factor activity
(1)
 
Sequence and Structure classification
SCOP fold  (1)
beta-Trefoil
(1)
 
SCOP family  (1)
Fibroblast growth factors (FGF)
(1)
 
CATH class  (1)
Mainly Beta
(1)
 
CATH topology  (1)
Trefoil (Acidic Fibroblast Growth Factor, subunit A)
(1)
 
Pfam accession / name  (1)
PF00167 : FGF
(1)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(1)
 
Diffraction radiation source type  (1)
Synchrotron
(1)
 
Diffraction source  (1)
NSLS BEAMLINE X4A
(1)
 
Synchrotron site  (1)
NSLS
(1)
 
Diffraction detector type  (1)
CCD
(1)
 
Refinement software  (1)
CNS
(1)
 
Representative Structures
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Crystal Structure of Fibroblast growth factor (FGF)8b in complex with FGF Receptor (FGFR) 2c
Mohammadi M, Olsen SK
Genes Dev (2006) [PMID: 16384934  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: Fibroblast growth factor receptor 2 and Fibroblast growth factor 8 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-149428 (Preferred)   search this ID
PDBe-KB: P55075    P55075    P21802   
X-ray diffraction
2.28Å resolution
Released: 7 Feb 2006
Model geometry
Fit model/data
2fdb
2fdb
2fdb
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