Uniprot accession / id : P56696  OR   Uniprot accession / id : B3KQH8  OR   Uniprot accession / id : Q9JK97
 
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Entry Information
Entry status  (1)
REL
(13)
 
Experimental methods  (2)
X-ray diffraction
(7)
Electron Microscopy
(6)
 
Authors  (33)
Minor DL
(6)
Chang A
(5)
Abderemane-Ali F
(4)
Gate RE
(4)
Hura GL
(4)
Rossen ND
(4)
Chen Y
(3)
Dong S
(3)
Li GL
(3)
Li T
(3)
Liu H
(3)
Shen H
(3)
Shu Y
(3)
Wang F
(3)
Wang S
(3)
Wang Y
(3)
Wu K
(3)
Xu F
(3)
Yue Z
(3)
Zhang F
(3)
Zheng Y
(3)
Archer CR
(1)
Bhattacharya A
(1)
Clark KA
(1)
De la Rosa V
(1)
Enslow BT
(1)
Holton JM
(1)
Howard RJ
(1)
Minor Jr DL
(1)
Shapiro MS
(1)
Taylor AB
(1)
Tolia A
(1)
Xu Q
(1)
 
Homo / hetero assembly  (2)
hetero
(12)
homo
(1)
 
Assembly composition  (2)
protein/protein complex
(12)
protein structure
(1)
 
Assembly polymer count  (4)
octamer
(6)
dimer
(5)
tetramer
(1)
trimer
(1)
 
Resolution distribution
2.0 - 2.5
(7)
2.5 - 3
(4)
3.0 - 3.5
(2)
 
Release year distribution
2005 - 2010
(1)
2010 - 2015
(1)
2015 - 2020
(8)
2020 - 2025
(6)
 
Journal  (4)
Neuron
(8)
Mol Cell
(3)
J Biol Chem
(1)
J Mol Biol
(1)
 
Macromolecules
Organism superkingdom  (2)
Eukaryota
(13)
Bacteria
(3)
 
Organism name  (3)
Homo sapiens
(13)
Aequorea victoria
(3)
Escherichia coli BL21(DE3)
(3)
 
Molecule name  (5)
KQT-like 4
(13)
Potassium channel subunit alpha KvLQT4
(13)
Potassium voltage-gated channel subfamily KQT member 4
(13)
Voltage-gated potassium channel subunit Kv7.4
(13)
Green fluorescent protein
(3)
 
Molecule type  (1)
Protein
(13)
 
Gene names  (2)
KCNQ4
(13)
GFP
(3)
 
Interacting Molecules  (3)
Calmodulin-1
(6)
Calmodulin-3
(6)
Potassium voltage-gated channel subfamily KQT member 4
(1)
 
Representative Structures
Representative Structures
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Entries 1 to 10 of 13
Entries 1 to 10 of 13
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Crystal Structure of the Ca2+/CaM:Kv7.4 (KCNQ4) AB Domain Complex, 1 mM CaCl2 soak
Chang A, Minor DL
Neuron (2018) [PMID: 29429937  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: CA    CA    SO4   
Assembly name: Potassium voltage-gated channel subfamily KQT member 4 and Calmodulin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-143929 (Preferred)   search this ID
PDBe-KB: P56696    P0DP23   
X-ray diffraction
2.3Å resolution
Released: 14 Mar 2018
Model geometry
Fit model/data
6b8m
6b8m
6b8m
Crystal Structure of the Apo/CaM:Kv7.4 (KCNQ4) AB Domain Complex
Chang A, Abderemane-Ali F, Minor DL
Neuron (2018) [PMID: 29429937  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: SO4   
Assembly name: Potassium voltage-gated channel subfamily KQT member 4 and Calmodulin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-143929 (Preferred)   search this ID
PDBe-KB: P56696    P0DP23   
X-ray diffraction
2.3Å resolution
Released: 14 Mar 2018
Model geometry
Fit model/data
6b8l
6b8l
6b8l
Crystal Structure of the Mg2+/CaM:Kv7.4 (KCNQ4) AB domain complex
Chang A, Minor DL
Neuron (2018) [PMID: 29429937  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: MG    SO4    MG   
Assembly name: Potassium voltage-gated channel subfamily KQT member 4 and Calmodulin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-143929 (Preferred)   search this ID
PDBe-KB: P56696    P0DP23   
X-ray diffraction
2.2Å resolution
Released: 14 Mar 2018
Model geometry
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6b8p
6b8p
6b8p
Crystal Structure of the Ca2+/CaM:Kv7.4 (KCNQ4) AB Domain Complex, 10 uM CaCl2 soak
Chang A, Minor DL
Neuron (2018) [PMID: 29429937  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: CA    CA    SO4   
Assembly name: Potassium voltage-gated channel subfamily KQT member 4 and Calmodulin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-143929 (Preferred)   search this ID
PDBe-KB: P56696    P0DP23   
X-ray diffraction
2.201Å resolution
Released: 14 Mar 2018
Model geometry
Fit model/data
6b8n
6b8n
6b8n
Cryo-EM structure of human KCNQ4
Shen H, Li T, Yue Z
Mol Cell (2021) [PMID: 33238160  ]
Assembly composition: protein/protein complex
Bound ligands: K    K    PT5   
Assembly name: Green fluorescent protein, Potassium voltage-gated channel subfamily KQT member 4 and Calmodulin-3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-144006 (Preferred)   search this ID
PDBe-KB: P56696    P42212    P0DP25   
Electron Microscopy
2.5Å resolution
Released: 2 Dec 2020
Model geometry
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Data not analysed
7byl
7byl
7byl
Cryo-EM structure of human KCNQ4 with retigabine
Shen H, Li T, Yue Z
Mol Cell (2021) [PMID: 33238160  ]
Assembly composition: protein/protein complex
Bound ligands: K    K    FBX    PT5   
Assembly name: Green fluorescent protein, Potassium voltage-gated channel subfamily KQT member 4 and Calmodulin-3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-144006 (Preferred)   search this ID
PDBe-KB: P56696    P42212    P0DP25   
Electron Microscopy
3.1Å resolution
Released: 2 Dec 2020
Model geometry
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Data not analysed
7bym
7bym
7bym
Cryo-EM structure of human KCNQ4 with linopirdine
Shen H, Li T, Yue Z
Mol Cell (2021) [PMID: 33238160  ]
Assembly composition: protein/protein complex
Bound ligands: K    FCC    K    PT5   
Assembly name: Green fluorescent protein, Potassium voltage-gated channel subfamily KQT member 4 and Calmodulin-3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-144006 (Preferred)   search this ID
PDBe-KB: P56696    P42212    P0DP25   
Electron Microscopy
3.3Å resolution
Released: 2 Dec 2020
Model geometry
Fit model/data
Data not analysed
7byn
7byn
7byn
Crystal structure of the Ca2+/CaM complex with independent peptides of Kv7.4 (KCNQ4) A & B domains
Taylor AB, Archer CR, Shapiro MS
J Biol Chem (2019) [PMID: 30808708  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: CA    CA   
Assembly name: Potassium voltage-gated channel subfamily KQT member 4 and Calmodulin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-143930 (Preferred)   search this ID
PDBe-KB: P56696    P0DP23   
X-ray diffraction
2.15Å resolution
Released: 13 Mar 2019
Model geometry
Data not analysed
Fit model/data
Data not analysed
6n5w
6n5w
6n5w
Crystal structure of a coiled-coil tetramerization domain from Kv7.4 channels
Howard RJ, Clark KA, Holton JM, Minor DL
Neuron (2007) [PMID: 17329207  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Potassium voltage-gated channel subfamily KQT member 4 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-157527 (Preferred)   search this ID
PDBe-KB: P56696   
X-ray diffraction
2.07Å resolution
Released: 13 Mar 2007
Model geometry
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2ovc
2ovc
2ovc
Crystal Structure of Ca2+/CaM:Kv7.4 (KCNQ4) B helix complex
Xu Q, Chang A, Tolia A, Minor Jr DL
J Mol Biol (2013) [PMID: 23178170  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: CA    CA   
Assembly name: Potassium voltage-gated channel subfamily KQT member 4 and Calmodulin-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-143929 (Preferred)   search this ID
PDBe-KB: P56696    P0DP23   
X-ray diffraction
2.6Å resolution
Released: 12 Dec 2012
Model geometry
Fit model/data
4gow
4gow
4gow
Entries 1 to 10 of 13
Entries 1 to 10 of 13