Uniprot accession / id : Q07954  OR   Uniprot accession / id : Q59FG2  OR   Uniprot accession / id : Q3U454  OR   Uniprot accession / id : Q91ZX7  OR   Uniprot accession / id : A1Z7C4  OR   Uniprot accession / id : Q7PV66
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Entry Information
Entry status  (1)
REL
(7)
 
Experimental methods  (2)
Solution NMR
(6)
X-ray diffraction
(1)
 
Authors  (23)
Dolmer K
(3)
Gettins PG
(3)
Gettins PGW
(3)
Huang W
(3)
Andersen OM
(2)
Bjerrum-Bohr I
(2)
Bonvin AM
(2)
Domaille PJ
(2)
Etzerodt M
(2)
Guttman M
(2)
Handel TM
(2)
Jensen GA
(2)
Komives EA
(2)
Kragelund BB
(2)
O'Shea C
(2)
O'shea C
(2)
Poulsen FM
(2)
Prieto JH
(2)
Thøgersen HC
(2)
Komives E
(1)
Simonovic M
(1)
Strickland DK
(1)
Volz K
(1)
 
Homo / hetero assembly  (2)
homo
(6)
hetero
(1)
 
Assembly composition  (2)
protein structure
(6)
protein/protein complex
(1)
 
Assembly polymer count  (2)
monomer
(6)
dimer
(1)
 
Resolution distribution
1.5 - 2
(1)
 
Release year distribution
1995 - 2000
(2)
2000 - 2005
(2)
2005 - 2010
(4)
2010 - 2015
(2)
 
Journal  (3)
J Mol Biol
(4)
J Biol Chem
(2)
Biochemistry
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(7)
 
Organism name  (1)
Homo sapiens
(7)
 
Molecule name  (14)
A2MR
(7)
APOER
(7)
Alpha-2-macroglobulin receptor
(7)
Apolipoprotein E receptor
(7)
LRP-1
(7)
LRP-515
(7)
LRP-85
(7)
LRPICD
(7)
Low-density lipoprotein receptor-related protein 1 515 kDa subunit
(7)
Low-density lipoprotein receptor-related protein 1 85 kDa subunit
(7)
Low-density lipoprotein receptor-related protein 1 intracellular domain
(7)
Prolow-density lipoprotein receptor-related protein 1
(7)
Apo-E
(1)
Apolipoprotein E
(1)
 
Molecule type  (1)
Protein
(7)
 
Gene names  (4)
A2MR
(7)
APR
(7)
LRP1
(7)
APOE
(1)
 
Interacting Molecules  (1)
Alpha-2-macroglobulin receptor-associated protein
(1)
 
Interacting ligands  (1)
CA : CALCIUM ION
(6)
 
Representative Structures
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Entries 1 to 7 of 7
Entries 1 to 7 of 7
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2knx
Solution Structure of complement repeat CR17 from LRP-1
Guttman M, Komives E
J Mol Biol (2010) [PMID: 20303980  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: CA    CA   
Assembly name: Low-density lipoprotein receptor-related protein 1 515 kDa subunit (Preferred)   search this complex
PDBe complex ID: PDB-CPX-170571 (Preferred)   search this ID
PDBe-KB: Q07954   
Solution NMR
Released: 14 Apr 2010
DOI: 10.2210/pdb2knx  
Model geometry
Fit model/data
Data not analysed
2knx
2knx
2knx
1j8e
Crystal structure of ligand-binding repeat CR7 from LRP
Simonovic M, Dolmer K, Huang W, Strickland DK, Volz K, Gettins PGW
Biochemistry (2001) [PMID: 11735395  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: CA    CA   
Assembly name: Low-density lipoprotein receptor-related protein 1 515 kDa subunit (Preferred)   search this complex
PDBe complex ID: PDB-CPX-170571 (Preferred)   search this ID
PDBe-KB: Q07954   
X-ray diffraction
1.85Å resolution
Released: 19 Dec 2001
DOI: 10.2210/pdb1j8e  
Model geometry
Fit model/data
1j8e
1j8e
1j8e
2kny
Fusion construct of CR17 from LRP-1 and ApoE residues 130-149
Guttman M, Komives EA
J Mol Biol (2010) [PMID: 20303980  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: CA    CA   
Assembly name: Apolipoprotein E, Low-density lipoprotein receptor-related protein 1 515 kDa subunit (Preferred)   search this complex
PDBe complex ID: PDB-CPX-135990 (Preferred)   search this ID
PDBe-KB: P02649    Q07954   
Solution NMR
Released: 14 Apr 2010
DOI: 10.2210/pdb2kny  
Model geometry
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Data not analysed
2kny
2kny
2kny
2fyl
Haddock model of the complex between double module of LRP, CR56, and first domain of receptor associated protein, RAP-d1.
Jensen GA, Andersen OM, Bonvin AM, Bjerrum-Bohr I, Etzerodt M, O'shea C, Poulsen FM, Kragelund BB
J Mol Biol (2006) [PMID: 16938309  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: CA    CA   
Assembly name: Prolow-density lipoprotein receptor-related protein 1 complex and Alpha-2-macroglobulin receptor-associated protein (Preferred)   search this complex
PDBe complex ID: PDB-CPX-151759 (Preferred)   search this ID
PDBe-KB: Q07954    P30533   
Solution NMR
Released: 10 Oct 2006
DOI: 10.2210/pdb2fyl  
Model geometry
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Data not analysed
2fyl
2fyl
2fyl
2fyj
NMR Solution structure of calcium-loaded LRP double module
Jensen GA, Andersen OM, Bonvin AM, Bjerrum-Bohr I, Etzerodt M, O'shea C, Poulsen FM, Kragelund BB
J Mol Biol (2006) [PMID: 16938309  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Low-density lipoprotein receptor-related protein 1 515 kDa subunit (Preferred)   search this complex
PDBe complex ID: PDB-CPX-170571 (Preferred)   search this ID
PDBe-KB: Q07954   
Solution NMR
Released: 10 Oct 2006
DOI: 10.2210/pdb2fyj  
Model geometry
Fit model/data
Data not analysed
2fyj
2fyj
2fyj
1cr8
LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN COMPLEMENT REPEAT 8
Huang W, Dolmer K, Gettins PGW
J Biol Chem (1999) [PMID: 10318830  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: CA    CA   
Assembly name: Low-density lipoprotein receptor-related protein 1 515 kDa subunit (Preferred)   search this complex
PDBe complex ID: PDB-CPX-170571 (Preferred)   search this ID
PDBe-KB: Q07954   
Solution NMR
Released: 23 Dec 1998
DOI: 10.2210/pdb1cr8  
Model geometry
Fit model/data
Data not deposited
1cr8
1cr8
1cr8
1d2l
NMR SOLUTION STRUCTURE OF COMPLEMENT-LIKE REPEAT CR3 FROM THE LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN (LRP). EVIDENCE FOR SPECIFIC BINDING TO THE RECEPTOR BINDING DOMAIN OF HUMAN ALPHA-2 MACROGLOBULIN
Dolmer K, Huang W, Gettins PGW
J Biol Chem (2000) [PMID: 10652313  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: CA    CA   
Assembly name: Low-density lipoprotein receptor-related protein 1 515 kDa subunit (Preferred)   search this complex
PDBe complex ID: PDB-CPX-170571 (Preferred)   search this ID
PDBe-KB: Q07954   
Solution NMR
Released: 14 Jan 2000
DOI: 10.2210/pdb1d2l  
Model geometry
Fit model/data
Data not analysed
1d2l
1d2l
1d2l
Entries 1 to 7 of 7
Entries 1 to 7 of 7