Entry status  (1)

REL

(35)

Experimental methods  (3)

Electron Microscopy

(31)

X-ray diffraction

(3)

Solution NMR

(1)

Authors  (57)

Accardi A

(8)

Agarwal S

(8)

Kim ED

(8)

Lee S

(8)

MacKinnon R

(8)

Nimigean C

(8)

Nimigean CM

(8)

Simon A

(8)

Nureki O

(7)

Tao X

(7)

Yamanouchi D

(7)

Chowdhury S

(5)

Pal K

(5)

Kallure GS

(4)

Jin MS

(3)

Kim S

(3)

Lee N

(3)

Lee NY

(3)

Park CS

(3)

Zhao C

(3)

Kallure G

(2)

Kim HJ

(2)

Kim YC

(2)

Kim YG

(2)

Lee EY

(2)

Park S

(2)

Park SB

(2)

Roh EC

(2)

Yuan P

(2)

Ahn JH

(1)

Budelli G

(1)

Butler A

(1)

Cui J

(1)

Deng Z

(1)

Geng Y

(1)

Hsiung Y

(1)

Jeong P

(1)

Jiang Y

(1)

Jo H

(1)

Leonetti MD

(1)

Lind J

(1)

Magleby KL

(1)

Maler L

(1)

Mäler L

(1)

Pagire HS

(1)

Pagire SH

(1)

Papadopoulos E

(1)

Pico AR

(1)

Salkoff L

(1)

Tonggu L

(1)

Unnerstale S

(1)

Unnerståle S

(1)

Wang L

(1)

Wu Y

(1)

Yang Y

(1)

Ye S

(1)

Zhang G

(1)

Homo / hetero assembly  (2)

homo

(18)

hetero

(17)

Assembly composition  (2)

protein structure

(18)

protein/protein complex

(17)

Assembly polymer count  (4)

octamer

(16)

tetramer

(15)

monomer

(3)

dimer

(1)

Resolution distribution

1.5 - 2

(1)

2.0 - 2.5

(1)

2.5 - 3

(12)

3.0 - 3.5

(11)

3.5 - 4

(9)

Release year distribution

2005 - 2010

(3)

2010 - 2015

(2)

2015 - 2020

(6)

2020 - 2025

(28)

2025 - 2030

(10)

Journal  (9)

To be published

(13)

Nat Commun

(8)

Elife

(4)

Proc Natl Acad Sci U S A

(4)

J Med Chem

(2)

Biochemistry

(1)

Life Sci Alliance

(1)

Nature

(1)

Science

(1)

Organism superkingdom  (1)

Eukaryota

(35)

Organism name  (1)

Homo sapiens

(35)

Molecule name  (13)

BK channel

(35)

BKCA alpha

(35)

Calcium-activated potassium channel subunit alpha-1

(35)

Calcium-activated potassium channel, subfamily M subunit alpha-1

(35)

K(VCA)alpha

(35)

KCa1.1

(35)

Maxi K channel

(35)

MaxiK

(35)

Slo homolog

(35)

Slo-alpha

(35)

Slo1

(35)

Slowpoke homolog

(35)

hSlo

(35)

Molecule type  (1)

Protein

(35)

Gene names  (3)

KCNMA

(35)

KCNMA1

(35)

SLO

(35)

Interacting Molecules  (3)

Calcium-activated potassium channel subunit beta-4

(10)

KCNMB2 ball/chain domain-containing protein

(8)

Leucine-rich repeat-containing protein 26

(7)

Interacting ligands  (13)

CA : CALCIUM ION

(19)

K : POTASSIUM ION

(16)

CLR : CHOLESTEROL

(14)

MG : MAGNESIUM ION

(14)

POV : (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate

(14)

AJP : Digitonin

(4)

Y01 : CHOLESTEROL HEMISUCCINATE

(3)

PGW : (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate

(2)

SO4 : SULFATE ION

(2)

A1L04 : 4-[4-(4-chlorophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol

(1)

A1L4E : 5-azanyl-2-[2,3,5,6-tetrakis(fluoranyl)-4-(trifluoromethyl)phenoxy]phenol

(1)

A1L4F : 5-(5-morpholin-4-ylpentylamino)-2-[2,3,5,6-tetrakis(fluoranyl)-4-(trifluoromethyl)phenoxy]phenol

(1)

NA : SODIUM ION

(1)

Biological function  (9)

monoatomic ion channel activity

(15)

actin binding

(3)

calcium-activated potassium channel activity

(3)

large conductance calcium-activated potassium channel activity

(3)

metal ion binding

(3)

potassium channel activity

(3)

protein binding

(3)

voltage-gated potassium channel activity

(3)

DNA-binding transcription factor activity

(1)

Biological process  (17)

potassium ion transport

(21)

monoatomic ion transport

(17)

transmembrane transport

(15)

intracellular potassium ion homeostasis

(3)

micturition

(3)

monoatomic ion transmembrane transport

(3)

negative regulation of cell volume

(3)

positive regulation of apoptotic process

(3)

potassium ion transmembrane transport

(3)

regulation of membrane potential

(3)

response to calcium ion

(3)

response to carbon monoxide

(3)

response to hypoxia

(3)

response to osmotic stress

(3)

smooth muscle contraction involved in micturition

(3)

vasodilation

(3)

regulation of DNA-templated transcription

(1)

Biological cell component  (7)

membrane

(21)

apical plasma membrane

(3)

caveola

(3)

monoatomic ion channel complex

(3)

plasma membrane

(3)

postsynaptic membrane

(3)

voltage-gated potassium channel complex

(3)

Pfam accession / name  (5)

PF03493 : BK_channel_a

(34)

PF21014 : Slowpoke_C

(34)

PF22614 : Slo-like_RCK

(34)

PF00520 : Ion_trans

(31)

PF07885 : Ion_trans_2

(31)

Diffraction protocol  (2)

Single wavelength

(3)

MAD

(1)

Diffraction radiation source type  (1)

Synchrotron

(3)

Diffraction source  (4)

APS BEAMLINE 24-ID-C

(2)

APS BEAMLINE 23-ID-B

(1)

APS BEAMLINE 23-ID-D

(1)

NSLS BEAMLINE X29A

(1)

Synchrotron site  (2)

APS

(3)

NSLS

(1)

Diffraction detector type  (3)

CCD

(2)

Image plate

(1)

Pixel

(1)

Refinement software  (2)

PHENIX

(7)

REFMAC

(2)

EM microscope model  (2)

FEI TITAN KRIOS

(25)

TFS KRIOS

(6)

EM detector name  (4)

GATAN K3 (6k x 4k)

(14)

GATAN K3 BIOQUANTUM (6k x 4k)

(11)

GATAN K2 SUMMIT (4k x 4k)

(5)

FEI FALCON IV (4k x 4k)

(1)

NMR software packages  (5)

CYANA

(1)

NMRDraw

(1)

PROCHECK / PROCHECK-NMR

(1)

Sparky

(1)

VNMR

(1)

NMR Field Strength

700.0 - 800

(1)

800.0 - 900

(1)

Representative Structures

100%

95%

90%

70%

50%

40%

30%