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Entry status
(1)
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(3)
Electron Microscopy
(10)
X-ray diffraction
(7)
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(1)
Authors
(67)
Chesarino NM
(4)
Emerman M
(4)
Gross JD
(4)
Alvarez-Cabrera AL
(3)
Azumaya CM
(3)
Chen XS
(3)
Cheng Y
(3)
Echeverria I
(3)
Hou C
(3)
Ito F
(3)
Langley C
(3)
Langley CA
(3)
Li Y
(3)
Li YL
(3)
Mandal A
(3)
Rohr J
(3)
Tsodikov OV
(3)
Zhou ZH
(3)
Bravo J
(2)
Hu Y
(2)
Hyun J
(2)
Kim K
(2)
Kim TG
(2)
Kouno T
(2)
Matsuo H
(2)
Pathak VK
(2)
Shibata S
(2)
Shigematsu M
(2)
Warren AJ
(2)
Wolf M
(2)
Xiong Y
(2)
Arizaga F
(1)
Binning JM
(1)
Chen J
(1)
Cheng TC
(1)
Delviks-Frankenberry KA
(1)
Desimmie BA
(1)
Dong LY
(1)
Goger M
(1)
Guo YY
(1)
Gupta V
(1)
Huang ZW
(1)
Ito Y
(1)
Kim WY
(1)
Li Z
(1)
Liu HN
(1)
Liu S
(1)
Nguyen HC
(1)
Qiu XL
(1)
Rabbits TH
(1)
Rabbitts TH
(1)
Shigesada K
(1)
Shiriaeva A
(1)
Speck NA
(1)
Wang H
(1)
Wang J
(1)
Wang YS
(1)
Werner MH
(1)
Williams RL
(1)
Wu C
(1)
Yang H
(1)
Yang MJ
(1)
Yu Y
(1)
Zang Y
(1)
Zhang BL
(1)
Zhang K
(1)
Ziegler SJ
(1)
Homo / hetero assembly
(2)
hetero
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homo
(1)
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(4)
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(7)
protein/protein complex
(6)
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(4)
protein structure
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(8)
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(6)
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(5)
tetramer
(2)
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(1)
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hexamer
(1)
monomer
(1)
octamer
(1)
Resolution distribution
2.0 - 2.5
(1)
2.5 - 3
(5)
3.0 - 3.5
(4)
3.5 - 4
(4)
4.0 - 4.5
(3)
Release year distribution
1995 - 2000
(1)
2000 - 2005
(3)
2010 - 2015
(1)
2015 - 2020
(5)
2020 - 2025
(12)
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(8)
Nat Commun
(4)
Nature
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(3)
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(2)
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(2)
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Macromolecules
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(18)
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(1)
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(18)
Molecule name
(7)
CBF-beta
(18)
Core-binding factor subunit beta
(18)
PEA2-beta
(18)
PEBP2-beta
(18)
Polyomavirus enhancer-binding protein 2 beta subunit
(18)
SL3-3 enhancer factor 1 subunit beta
(18)
SL3/AKV core-binding factor beta subunit
(18)
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(1)
Protein
(18)
Gene names
(1)
CBFB
(18)
Interacting Molecules
(26)
Virion infectivity factor
(12)
Elongin-B
(8)
Elongin-C
(8)
DNA dC->dU-editing enzyme APOBEC-3G
(6)
Cullin-5
(3)
DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3')
(3)
DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3')
(3)
Runt-related transcription factor 2
(3)
Runt-related transcription factor 1
(2)
Transcriptional regulator ERG
(2)
DNA (5'-(*CP*AP*AP*CP*CP*GP*CP*AP*AP*C)-3')
(1)
DNA (5'-(*GP*TP*TP*GP*CP*GP*GP*TP*TP*G)-3')
(1)
DNA dC->dU-editing enzyme APOBEC-3F
(1)
DNA dC->dU-editing enzyme APOBEC-3H
(1)
Friend leukemia integration 1 transcription factor
(1)
RNA
(1)
RNA (5'-R(*CP*GP*GP*UP*UP*GP*AP*UP*CP*GP*UP*UP*UP*UP*AP*AP*CP*AP*A)-3')
(1)
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(1)
RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*A)-3')
(1)
RNA (5'-R(P*AP*AP*AP*AP*UP*AP*UP*U)-3')
(1)
RNA (5'-R(P*AP*AP*UP*AP*AP*AP*AP*AP*U)-3')
(1)
RNA (5'-R(P*UP*AP*AP*AP*UP*AP*UP*U)-3')
(1)
RNA (5'-R(P*UP*UP*UP*AP*AP*AP*AP*AP*U)-3')
(1)
RNA(5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
(1)
RNA(5'-R(AP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3')
(1)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
(1)
Function and Biology
Biological function
(4)
transcription coactivator activity
(18)
DNA binding
(6)
protein binding
(6)
sequence-specific DNA binding
(6)
Biological process
(13)
cell maturation
(6)
definitive hemopoiesis
(6)
lymphocyte differentiation
(6)
myeloid cell differentiation
(6)
negative regulation of CD4-positive, alpha-beta T cell differentiation
(6)
negative regulation of transcription by RNA polymerase II
(6)
ossification
(6)
osteoblast differentiation
(6)
positive regulation of CD8-positive, alpha-beta T cell differentiation
(6)
positive regulation of transcription by RNA polymerase II
(6)
protein polyubiquitination
(6)
regulation of transcription by RNA polymerase II
(6)
transcription by RNA polymerase II
(6)
Biological cell component
(4)
nucleus
(18)
core-binding factor complex
(6)
membrane
(6)
nucleoplasm
(6)
Sequence and Structure classification
SCOP fold
(1)
Core binding factor beta, CBF
(3)
SCOP family
(1)
Core binding factor beta, CBF
(3)
CATH class
(1)
Mainly Beta
(4)
CATH topology
(1)
Polyomavirus Enhancer Binding Protein 2; Chain: A;
(4)
Pfam accession / name
(1)
PF02312 : CBF_beta
(18)
Experimental Information
Diffraction protocol
(2)
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(6)
MAD
(1)
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(1)
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(7)
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(5)
APS BEAMLINE 22-ID
(3)
ALS BEAMLINE 8.3.1
(1)
ESRF BEAMLINE ID14-3
(1)
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(1)
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(1)
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(4)
APS
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ALS
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SSRF
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CCD
(6)
Pixel
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PHENIX
(7)
REFMAC
(4)
CNS
(2)
EM microscope model
(2)
FEI TITAN KRIOS
(9)
TFS GLACIOS
(1)
EM detector name
(5)
GATAN K3 (6k x 4k)
(3)
GATAN K3 BIOQUANTUM (6k x 4k)
(3)
FEI FALCON IV (4k x 4k)
(2)
FEI FALCON III (4k x 4k)
(1)
GATAN K2 SUMMIT (4k x 4k)
(1)
NMR
NMR software packages
(1)
X-PLOR
(1)
NMR Field Strength
400.0 - 500
(1)
500.0 - 600
(1)
600.0 - 700
(1)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
Entries 1 to 10 of 18
Select all entries on this page
Cryo-EM structure of APOBEC3G-Vif complex
Kouno T, Shibata S, Hyun J, Kim TG, Wolf M
Nat Commun
(2023)
[PMID: 37419875 ]
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-235797 (Preferred)
search this ID
Full-length APOBEC3G in complex with HIV-1 Vif, CBF-beta, and fork RNA
Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS
Sci Adv
(2023)
[PMID: 36598981 ]
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-223602 (Preferred)
search this ID
Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC monomeric complex
Li Y, Langley C, Azumaya CM, Echeverria I, Chesarino NM, Emerman M, Cheng Y, Gross JD
Nature
(2023)
[PMID: 36754086 ]
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-227153 (Preferred)
search this ID
Cryo-EM structure of APOBEC3G-Vif complex
Kouno T, Shibata S, Hyun J, Kim TG, Wolf M
Nat Commun
(2023)
[PMID: 37419875 ]
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-235796 (Preferred)
search this ID
Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 2
Li Y, Langley C, Azumaya CM, Echeverria I, Chesarino NM, Emerman M, Cheng Y, Gross JD
Nature
(2023)
[PMID: 36754086 ]
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-246640 (Preferred)
search this ID
Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 1
Li Y, Langley C, Azumaya CM, Echeverria I, Chesarino NM, Emerman M, Cheng Y, Gross JD
Nature
(2023)
[PMID: 36754086 ]
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-227154 (Preferred)
search this ID
Crystal structure of SIVrcm Vif-CBFbeta-ELOB-ELOC complex
Binning JM, Chesarino NM, Emerman M, Gross JD
Cell Host Microbe
(2019)
[PMID: 31830442 ]
Source organisms: Simian immunodeficiency virus , Homo sapiens
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-122739 (Preferred)
search this ID
cryoEM structure of the truncated HIV-1 Vif/CBFbeta/A3F complex
Hu Y, Xiong Y
Nat Struct Mol Biol
(2019)
[PMID: 31792451 ]
Source organisms: Human immunodeficiency virus 1 , Homo sapiens
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-146246 (Preferred)
search this ID
Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC
Hou C, Tsodikov OV
Structure
(2021)
[PMID: 33275876 ]
Source organism: Homo sapiens
Assembly composition: DNA/protein complex
PDBe complex ID:
PDB-CPX-120774 (Preferred)
search this ID
Aml1/cbf-beta/dna complex
Bravo J, Warren AJ
Nat Struct Biol
(2001)
[PMID: 11276260 ]
Source organisms: Synthetic construct, Homo sapiens
Assembly composition: DNA/protein complex
Assembly name:
Core-binding factor subunit beta and Runt-related transcription factor 1 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-113888 (Preferred)
search this ID
Entries 1 to 10 of 18