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(1)
X-ray diffraction
(4)
Authors
(18)
Nogi T
(3)
Takagi J
(3)
Yasui N
(3)
Hirai H
(2)
Tabata S
(2)
Yamamoto M
(2)
Yamashita K
(2)
Argiriadi MA
(1)
Deng K
(1)
Egan D
(1)
Gao L
(1)
Gizatullin F
(1)
Goodearl A
(1)
Harlan J
(1)
Karaoglu D
(1)
Karaoglu Hanzatian D
(1)
Qiu W
(1)
Villanueva R
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Homo / hetero assembly
(2)
hetero
(3)
homo
(1)
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(2)
protein/protein complex
(3)
protein structure
(1)
Assembly polymer count
(3)
dimer
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monomer
(1)
trimer
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Resolution distribution
1.5 - 2
(2)
2.5 - 3
(1)
3.0 - 3.5
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2005 - 2010
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To be published
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Front Drug Discov (Lausanne)
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Structure
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Eukaryota
(4)
Organism name
(1)
Homo sapiens
(4)
Molecule name
(3)
Apolipoprotein E receptor 2
(4)
LRP-8
(4)
Low-density lipoprotein receptor-related protein 8
(4)
Molecule type
(1)
Protein
(4)
Gene names
(2)
APOER2
(4)
LRP8
(4)
Interacting Molecules
(3)
Reelin
(2)
11H1 Fab Heavy chain
(1)
11H1 Fab Light chain
(1)
Interacting ligands
(3)
CA : CALCIUM ION
(3)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(1)
SO4 : SULFATE ION
(1)
Function and Biology
Biological function
(1)
calcium ion binding
(1)
Sequence and Structure classification
Pfam accession / name
(4)
PF00057 : Ldl_recept_a
(4)
PF00058 : Ldl_recept_b
(1)
PF07645 : EGF_CA
(1)
PF14670 : FXa_inhibition
(1)
Experimental Information
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(4)
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(4)
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(4)
ALBA BEAMLINE XALOC
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PHOTON FACTORY BEAMLINE BL-17A
(1)
PHOTON FACTORY BEAMLINE BL-5A
(1)
SPRING-8 BEAMLINE BL44XU
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SPring-8
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Representative Structures
Representative Structures
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Entries 1 to 4 of 4
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Crystal structure of the LA12 fragment of ApoER2
Nogi T, Tabata S, Hirai H, Yasui N, Takagi J
To be published
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Low-density lipoprotein receptor-related protein 8
(Preferred)
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PDBe complex ID:
PDB-CPX-171911 (Preferred)
search this ID
PDBe-KB:
Q14114
Crystal structure of the ApoER2 ectodomain in complex with the Reelin R56 fragment
Yasui N, Hirai H, Yamashita K, Takagi J, Nogi T
To be published
Source organisms: Mus musculus , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Reelin and Low-density lipoprotein receptor-related protein 8
(Preferred)
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PDBe complex ID:
PDB-CPX-171912 (Preferred)
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Structural basis for specific recognition of reelin by its receptors
Yasui N, Nogi T, Takagi J
Structure
(2010)
[PMID: 20223215 ]
Source organisms: Mus musculus , Homo sapiens
Assembly composition: protein/protein complex
Carbohydrate polymer components:
Molecule 1 -
NAG(2)
Assembly name:
Reelin and Low-density lipoprotein receptor-related protein 8
(Preferred)
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PDBe complex ID:
PDB-CPX-171912 (Preferred)
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LRP8 11H1 Fab complexed to a cyclized CR1 peptide
Argiriadi MA, Deng K, Egan D, Gao L, Gizatullin F, Harlan J, Karaoglu D, Qiu W, Goodearl A
Front Drug Discov (Lausanne)
(2023)
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Bound ligands:
SO4
Assembly name:
Low-density lipoprotein receptor-related protein 8 and IG-heavy chain and IG-light kappa chain
(Preferred)
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PDBe complex ID:
PDB-CPX-233661 (Preferred)
search this ID
PDBe-KB:
Q14114
Entries 1 to 4 of 4