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X-ray diffraction
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(23)
Bubeck D
(3)
Graham SC
(3)
Jackson AP
(3)
Jones EY
(3)
Reijns MA
(3)
Baillie GS
(2)
Gibson LC
(2)
Astell KR
(1)
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(1)
Chon H
(1)
Crouch RJ
(1)
Cybulska M
(1)
Figiel M
(1)
Gao N
(1)
Harvey S
(1)
Hollis T
(1)
Li N
(1)
Li Q
(1)
Nowotny M
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Perrino FW
(1)
Shaban N
(1)
Shaban NM
(1)
Tian Y
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hetero
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protein/protein complex
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trimer
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hexamer
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2.5 - 3
(3)
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2005 - 2010
(4)
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(6)
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(7)
RNase H2 subunit B
(6)
Ribonuclease H2 subunit B
(6)
Ribonuclease HI subunit B
(6)
AGS2
(4)
Aicardi-Goutieres syndrome 2 protein
(4)
Deleted in lymphocytic leukemia 8
(4)
Deleted in lymphocytic leukemia 8 homolog
(2)
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(6)
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DLEU8
(4)
RNASEH2B
(4)
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(2)
Rnaseh2b
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Interacting Molecules
(7)
Ribonuclease H2 subunit A
(5)
Ribonuclease H2 subunit C
(5)
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(2)
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Function and Biology
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3.1.26.4 : Ribonuclease H
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in utero embryonic development
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mismatch repair
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negative regulation of gene expression
(3)
positive regulation of fibroblast proliferation
(3)
regulation of DNA damage checkpoint
(3)
regulation of G2/M transition of mitotic cell cycle
(3)
ribonucleotide metabolic process
(3)
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ribonuclease H2 complex
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nucleoplasm
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nucleus
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Histone, subunit A
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N-terminal domain of TfIIb
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PF09468 : RNase_H2-Ydr279
(5)
PF17745 : Ydr279_N
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DIAMOND BEAMLINE I03
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GATAN K3 (6k x 4k)
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Representative Structures
Representative Structures
Entries
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Entries 1 to 6 of 6
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Structure of the human endogenous PCNA-FEN1-RNase H2 complex - State D
Tian Y, Gao N
EMBO J
(2024)
[PMID: 39578540 ]
Source organism: Homo sapiens
Assembly composition: DNA/protein complex
Assembly name:
PCNA homotrimer and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-281327 (Preferred)
search this ID
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Bubeck D, Graham SC, Jones EY
J Biol Chem
(2011)
[PMID: 21177854 ]
Source organism: Mus musculus
Assembly composition: protein/protein complex
Assembly name:
RNase H2 complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-182412 (Preferred)
search this ID
Structure of human PCNA bound to RNASEH2B PIP box peptide
Bubeck D, Reijns MA, Graham SC, Astell KR, Jones EY, Jackson AP
Nucleic Acids Res
(2011)
[PMID: 21245041 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
PCNA homotrimer and Ribonuclease H2 subunit B
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-146061 (Preferred)
search this ID
mouse RNase H2 complex
Shaban N, Harvey S, Perrino FW, Hollis T
J Biol Chem
(2010)
[PMID: 19923215 ]
Source organism: Mus musculus
Assembly composition: protein/protein complex
Assembly name:
RNase H2 complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-182412 (Preferred)
search this ID
Crystal structure of human RNase H2 complex
Figiel M, Chon H, Cerritelli SM, Cybulska M, Crouch RJ, Nowotny M
J Biol Chem
(2011)
[PMID: 21177858 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
RNase H2 complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131120 (Preferred)
search this ID
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
Bubeck D, Graham SC, Jones EY
J Biol Chem
(2011)
[PMID: 21177854 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
RNase H2 complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131120 (Preferred)
search this ID
Entries 1 to 6 of 6