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Solution NMR
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Authors
(9)
Blanco FJ
(1)
Campos-Olivas R
(1)
Diercks T
(1)
Marcaida MJ
(1)
Montoya G
(1)
Pantoja-Uceda D
(1)
Prieto J
(1)
Sanchez R
(1)
Sánchez R
(1)
Homo / hetero assembly
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homo
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protein structure
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monomer
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Release year distribution
2005 - 2010
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J Biol Chem
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Macromolecules
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Eukaryota
(1)
Organism name
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Homo sapiens
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Molecule name
(3)
DDIT-1
(1)
DNA damage-inducible transcript 1 protein
(1)
Growth arrest and DNA damage-inducible protein GADD45 alpha
(1)
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Gene names
(3)
DDIT1
(1)
GADD45
(1)
GADD45A
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Function and Biology
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kinase binding
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promoter-specific chromatin binding
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protein binding
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protein heterodimerization activity
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apoptotic process
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cellular response to ionizing radiation
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cellular response to mechanical stimulus
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centrosome cycle
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negative regulation of angiogenesis
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negative regulation of blood vessel endothelial cell migration
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negative regulation of peptidyl-serine phosphorylation of STAT protein
(1)
negative regulation of protein serine/threonine kinase activity
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negative regulation of transcription by RNA polymerase II
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positive regulation of JNK cascade
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positive regulation of apoptotic process
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positive regulation of p38MAPK cascade
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positive regulation of reactive oxygen species metabolic process
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regulation of cell cycle
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regulation of cyclin-dependent protein serine/threonine kinase activity
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signal transduction in response to DNA damage
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Three-dimensional structure of human Gadd45alpha in solution by NMR
Sanchez R, Pantoja-Uceda D, Prieto J, Diercks T, Campos-Olivas R, Blanco FJ
J Biol Chem
(2010)
[PMID: 20460379 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Growth arrest and DNA damage-inducible protein GADD45 alpha
(Preferred)
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PDBe complex ID:
PDB-CPX-150240 (Preferred)
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