Uniprot accession / id : Q5TCA8  OR   Uniprot accession / id : P24522  OR   Uniprot accession / id : Q3ZBN6  OR   Uniprot accession / id : P48316  OR   Uniprot accession / id : Q3UMH6  OR   Uniprot accession / id : Q66HL6  OR   Uniprot accession / id : Q6GMM1  OR   Uniprot accession / id : Q6NYS7
 
Filter by :
Entry Information
Entry status  (1)
REL
(1)
 
Experimental methods  (1)
Solution NMR
(1)
 
Authors  (9)
Blanco FJ
(1)
Campos-Olivas R
(1)
Diercks T
(1)
Marcaida MJ
(1)
Montoya G
(1)
Pantoja-Uceda D
(1)
Prieto J
(1)
Sanchez R
(1)
Sánchez R
(1)
 
Homo / hetero assembly  (1)
homo
(1)
 
Assembly composition  (1)
protein structure
(1)
 
Assembly polymer count  (1)
monomer
(1)
 
Release year distribution
2005 - 2010
(1)
 
Journal  (1)
J Biol Chem
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(1)
 
Organism name  (1)
Homo sapiens
(1)
 
Molecule name  (3)
DDIT-1
(1)
DNA damage-inducible transcript 1 protein
(1)
Growth arrest and DNA damage-inducible protein GADD45 alpha
(1)
 
Molecule type  (1)
Protein
(1)
 
Gene names  (3)
DDIT1
(1)
GADD45
(1)
GADD45A
(1)
 
Function and Biology
Biological function  (5)
kinase binding
(1)
promoter-specific chromatin binding
(1)
protein binding
(1)
protein heterodimerization activity
(1)
protein homodimerization activity
(1)
 
Biological process  (18)
DNA damage response
(1)
DNA repair
(1)
apoptotic process
(1)
cellular response to ionizing radiation
(1)
cellular response to mechanical stimulus
(1)
centrosome cycle
(1)
negative regulation of angiogenesis
(1)
negative regulation of blood vessel endothelial cell migration
(1)
negative regulation of peptidyl-serine phosphorylation of STAT protein
(1)
negative regulation of protein serine/threonine kinase activity
(1)
negative regulation of transcription by RNA polymerase II
(1)
positive regulation of JNK cascade
(1)
positive regulation of apoptotic process
(1)
positive regulation of p38MAPK cascade
(1)
positive regulation of reactive oxygen species metabolic process
(1)
regulation of cell cycle
(1)
regulation of cyclin-dependent protein serine/threonine kinase activity
(1)
signal transduction in response to DNA damage
(1)
 
Representative Structures
Representative Structures
100%
95%
90%
70%
50%
40%
30%
Entries 1 to 1 of 1
Entries 1 to 1 of 1
 Select all entries on this page
Three-dimensional structure of human Gadd45alpha in solution by NMR
Sanchez R, Pantoja-Uceda D, Prieto J, Diercks T, Campos-Olivas R, Blanco FJ
J Biol Chem (2010) [PMID: 20460379  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Growth arrest and DNA damage-inducible protein GADD45 alpha (Preferred)   search this complex
PDBe complex ID: PDB-CPX-150240 (Preferred)   search this ID
PDBe-KB: P24522   
Solution NMR
Released: 31 Mar 2009
Model geometry
Fit model/data
Data not analysed
2kg4
2kg4
2kg4
Entries 1 to 1 of 1
Entries 1 to 1 of 1