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Entry status
(1)
Experimental methods
(2)
Solution NMR
(4)
X-ray diffraction
(2)
Authors
(29)
Adams ME
(3)
Froehner SC
(3)
Long JF
(3)
Wen W
(3)
Xu W
(3)
Yan J
(3)
Zhang M
(3)
Ashurst J
(1)
Bredt DS
(1)
Christopherson KS
(1)
Harwood I
(1)
Harwood IM
(1)
Hillier BJ
(1)
Hoffmueller U
(1)
Hoffmuller U
(1)
Hoffmüller U
(1)
Karpiak J
(1)
Kortemme T
(1)
Krause G
(1)
Lim WA
(1)
Macias M
(1)
Macias MJ
(1)
Melero C
(1)
Ollikainen N
(1)
Oschkinat H
(1)
Prehoda KE
(1)
Schmieder P
(1)
Schneider-Mergener J
(1)
Schultz J
(1)
Homo / hetero assembly
(2)
hetero
(3)
homo
(3)
Assembly composition
(2)
protein structure
(3)
protein/protein complex
(3)
Assembly polymer count
(2)
dimer
(3)
monomer
(3)
Resolution distribution
1.5 - 2
(1)
2.0 - 2.5
(1)
Release year distribution
1995 - 2000
(2)
2005 - 2010
(3)
2010 - 2015
(1)
Journal
(4)
EMBO J
(3)
Nat Struct Biol
(1)
Proc Natl Acad Sci U S A
(1)
Science
(1)
Macromolecules
Organism superkingdom
(1)
Eukaryota
(6)
Organism name
(2)
Mus musculus
(6)
Rattus norvegicus
(2)
Molecule name
(13)
59 kDa dystrophin-associated protein A1 acidic component 1
(6)
Alpha-1-syntrophin
(6)
Syntrophin-1
(6)
Constitutive NOS
(2)
N-NOS
(2)
NC-NOS
(2)
NOS type I
(2)
Neuronal NOS
(2)
Nitric oxide synthase 1
(2)
Nitric oxide synthase, brain
(2)
Peptidyl-cysteine S-nitrosylase NOS1
(2)
bNOS
(2)
nNOS
(2)
Molecule type
(1)
Protein
(6)
Gene names
(4)
Snt1
(6)
Snta1
(6)
Bnos
(2)
Nos1
(2)
Interacting Molecules
(3)
Alpha-1-syntrophin
(2)
Nitric oxide synthase 1
(2)
PEPTIDE GVKESLV
(1)
Function and Biology
EC number / name
(1)
1.14.13.39 : Nitric-oxide synthase (NADPH)
(2)
Biological function
(1)
structural molecule activity
(6)
Sequence and Structure classification
SCOP fold
(2)
PDZ domain-like
(3)
PH domain-like barrel
(1)
SCOP family
(2)
PDZ domain
(3)
Pleckstrin-homology domain (PH domain)
(1)
CATH class
(1)
Mainly Beta
(6)
CATH topology
(2)
Pdz3 Domain
(5)
PH-domain like
(2)
Pfam accession / name
(2)
PF00595 : PDZ
(5)
PF18012 : PH_17
(2)
Experimental Information
Diffraction protocol
(1)
Single wavelength
(2)
Diffraction radiation source type
(1)
Synchrotron
(2)
Diffraction source
(3)
ALS BEAMLINE 5.0.2
(1)
ALS BEAMLINE 8.3.1
(1)
SSRL BEAMLINE BL7-1
(1)
Synchrotron site
(2)
ALS
(2)
SSRL
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REFMAC
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X-PLOR
(1)
NMR
NMR software packages
(2)
CNS
(3)
X-PLOR
(1)
NMR Field Strength
500.0 - 600
(1)
600.0 - 700
(1)
700.0 - 800
(4)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
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Entries 1 to 6 of 6
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Crystal structure of the computationally designed NNOS-Syntrophin complex
Harwood IM, Melero C, Ollikainen N, Kortemme T
Proc Natl Acad Sci U S A
(2014)
[PMID: 25313039 ]
Source organisms: Rattus norvegicus , Mus musculus
Assembly composition: protein/protein complex
Assembly name:
Nitric oxide synthase 1 and Alpha-1-syntrophin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-151519 (Preferred)
search this ID
Unexpected Modes of PDZ Domain Scaffolding Revealed by Structure of NNOS-Syntrophin Complex
Hillier BJ, Christopherson KS, Prehoda KE, Bredt DS, Lim WA
Science
(1999)
[PMID: 10221915 ]
Source organisms: Rattus norvegicus , Mus musculus
Assembly composition: protein/protein complex
Assembly name:
Nitric oxide synthase 1 and Alpha-1-syntrophin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-151519 (Preferred)
search this ID
Solution structure of the PDZ domain of alpha-syntrophin
Yan J, Xu W, Wen W, Long JF, Adams ME, Froehner SC, Zhang M
EMBO J
(2005)
[PMID: 16252003 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Alpha-1-syntrophin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-178874 (Preferred)
search this ID

solution structure of the joined PH domain of alpha1-syntrophin
Yan J, Wen W, Xu W, Long JF, Adams ME, Froehner SC, Zhang M
EMBO J
(2005)
[PMID: 16252003 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Alpha-1-syntrophin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-178874 (Preferred)
search this ID

solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Yan J, Xu W, Wen W, Long JF, Adams ME, Froehner SC, Zhang M
EMBO J
(2005)
[PMID: 16252003 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Alpha-1-syntrophin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-178874 (Preferred)
search this ID

SOLUTION STRUCTURE OF THE SYNTROPHIN PDZ DOMAIN IN COMPLEX WITH THE PEPTIDE GVKESLV, NMR, 15 STRUCTURES
Schultz J, Hoffmueller U, Ashurst J, Krause G, Schmieder P, Macias M, Schneider-Mergener J, Oschkinat H
Nat Struct Biol
(1998)
[PMID: 9437424 ]
Source organisms: Synthetic construct, Mus musculus
Assembly composition: protein/protein complex
Assembly name:
Alpha-1-syntrophin and peptide
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-163160 (Preferred)
search this ID

Entries 1 to 6 of 6