4n78

The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton

Chen ZC

Cell (2014) [PMID: 24439376  ]

Source organisms: Synthetic construct, Homo sapiens  

Assembly composition: protein/protein complex

Bound ligands: GOL    CL   

PDBe complex ID: PDB-CPX-164863 (Preferred)   search this ID

PDBe-KB: Q7L576    Q9Y2A7    Q92558    Q8WUW1    Q9NYB9   

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X-ray diffraction

2.43Å resolution

Released: 5 Feb 2014

DOI: 10.2210/pdb4n78  

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  3p8c

Structure and Control of the Actin Regulatory WAVE Complex

Chen Z, Borek D, Padrick SB, Gomez TS, Metlagel Z, Ismail AM, Umetani J, Billadeau DD, Otwinowski Z, Rosen MK

Nature (2010) [PMID: 21107423  ]

Source organism: Homo sapiens  

Assembly composition: protein/protein complex

Bound ligands: GOL    TRS    CL    TRS   

PDBe complex ID: PDB-CPX-181632 (Preferred)   search this ID

PDBe-KB: Q7L576    Q9Y2A7    Q92558    Q8WUW1    Q9NYB9   

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X-ray diffraction

2.29Å resolution

Released: 1 Dec 2010

DOI: 10.2210/pdb3p8c  

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  7usc

Cryo-EM structure of WAVE Regulatory Complex

Ding B, Yang S, Chen B, Chowdhury S

Nat Commun (2022) [PMID: 36114192  ]

Source organism: Homo sapiens  

Assembly composition: protein/protein complex

PDBe complex ID: PDB-CPX-181632 (Preferred)   search this ID

PDBe-KB: Q7L576    Q9Y2A7    Q92558    Q8WUW1    Q9NYB9   

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Electron Microscopy

3Å resolution

Released: 21 Sep 2022

DOI: 10.2210/pdb7usc  

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  7usd

Cryo-EM structure of D-site Rac1-bound WAVE Regulatory Complex

Ding B, Yang S, Chen B, Chowdhury S

Nat Commun (2022) [PMID: 36114192  ]

Source organism: Homo sapiens  

Assembly composition: protein/protein complex

Bound ligands: MG    GTP    GTP    MG   

PDBe complex ID: PDB-CPX-158904 (Preferred)   search this ID

PDBe-KB: Q7L576    P63000    Q9Y2A7    Q92558    Q8WUW1    Q9NYB9   

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Electron Microscopy

3Å resolution

Released: 21 Sep 2022

DOI: 10.2210/pdb7usd  

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  7use

Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site

Ding B, Yang S, Chen B, Chowdhury S

Nat Commun (2022) [PMID: 36114192  ]

Source organism: Homo sapiens  

Assembly composition: protein/protein complex

Bound ligands: GNP    MG    GTP    GNP    GTP    MG   

PDBe complex ID: PDB-CPX-158895 (Preferred)   search this ID

PDBe-KB: Q7L576    P63000    Q9Y2A7    Q92558    Q8WUW1    Q9NYB9   

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Electron Microscopy

3Å resolution

Released: 21 Sep 2022

DOI: 10.2210/pdb7use  

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