Uniprot accession / id : Q9H9A7  OR   Uniprot accession / id : A4IF98  OR   Uniprot accession / id : Q5ZHV8  OR   Uniprot accession / id : Q7ZVM9
 
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Entry Information
Entry status  (1)
REL
(7)
 
Experimental methods  (1)
X-ray diffraction
(7)
 
Authors  (35)
Wang W
(4)
Abdulrahman W
(2)
Bizard AH
(2)
Bocquet N
(2)
Bunker RD
(2)
Busygina V
(2)
Cavadini S
(2)
Cejka P
(2)
Faty M
(2)
Guo R
(2)
Hickson ID
(2)
Hoadley KA
(2)
Keck JL
(2)
Kowalczykowski SC
(2)
Larsen NB
(2)
Lei M
(2)
Meetei AR
(2)
Singh TR
(2)
Sung P
(2)
Thoma NH
(2)
Thomä NH
(2)
Wan K
(2)
Wang F
(2)
Xue Y
(2)
Yang Y
(2)
Fu W
(1)
Fu WM
(1)
Ling C
(1)
Satyshur KA
(1)
Takata M
(1)
Wu Y
(1)
Wu YY
(1)
Xu D
(1)
Zang N
(1)
Zhou C
(1)
 
Homo / hetero assembly  (2)
hetero
(6)
homo
(1)
 
Assembly composition  (2)
protein/protein complex
(6)
protein structure
(1)
 
Assembly polymer count  (3)
dimer
(5)
monomer
(1)
trimer
(1)
 
Resolution distribution
1.5 - 2
(4)
2.5 - 3
(1)
3.0 - 3.5
(2)
 
Release year distribution
2005 - 2010
(3)
2010 - 2015
(6)
2020 - 2025
(1)
 
Journal  (4)
Structure
(3)
Nat Struct Mol Biol
(2)
Elife
(1)
Proc Natl Acad Sci U S A
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(7)
 
Organism name  (1)
Homo sapiens
(7)
 
Molecule name  (4)
BLAP75
(7)
BLM-associated protein of 75 kDa
(7)
FAAP75
(7)
RecQ-mediated genome instability protein 1
(7)
 
Molecule type  (1)
Protein
(7)
 
Gene names  (2)
C9orf76
(7)
RMI1
(7)
 
Interacting Molecules  (4)
RecQ-mediated genome instability protein 2
(3)
DNA topoisomerase 3-alpha
(2)
Fanconi anemia group M protein
(1)
Replication protein A 70 kDa DNA-binding subunit, N-terminally processed
(1)
 
Interacting ligands  (1)
BEN : BENZAMIDINE
(1)
 
Function and Biology
Biological function  (1)
nucleotide binding
(3)
 
Sequence and Structure classification
CATH class  (3)
Mainly Beta
(6)
Mainly Alpha
(3)
Special
(3)
 
CATH topology  (3)
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
(6)
Helicase, Ruva Protein; domain 3
(3)
Helix Hairpins
(3)
 
Pfam accession / name  (3)
PF08585 : RMI1_N_C
(3)
PF16099 : RMI1_C
(3)
PF21000 : RMI1_N_N
(3)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(7)
 
Diffraction radiation source type  (1)
Synchrotron
(7)
 
Diffraction source  (4)
APS BEAMLINE 21-ID-D
(3)
SLS BEAMLINE X10SA
(2)
APS BEAMLINE 21-ID-F
(1)
SSRF BEAMLINE BL19U1
(1)
 
Synchrotron site  (3)
APS
(4)
SLS
(2)
SSRF
(1)
 
Diffraction detector type  (2)
CCD
(4)
Pixel
(3)
 
Representative Structures
Representative Structures
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Entries 1 to 7 of 7
Entries 1 to 7 of 7
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Crystal structure of RPA70N-RMI1 fusion
Wu YY, Zang N, Fu WM, Zhou C
Elife (2023) [PMID: 37668474  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: RecQ-mediated genome instability protein 1 and Replication protein A 70 kDa DNA-binding subunit, N-terminally processed (Preferred)   search this complex
PDBe complex ID: PDB-CPX-218083 (Preferred)   search this ID
PDBe-KB: Q9H9A7    P27694   
X-ray diffraction
1.6Å resolution
Released: 14 Jun 2023
Model geometry
Fit model/data
7xuv
7xuv
7xuv
Crystal structure of human RMI1C-RMI2 complex
Wang F, Yang Y, Singh TR, Busygina V, Guo R, Wan K, Wang W, Sung P, Meetei AR, Lei M
Structure (2010) [PMID: 20826342  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Modified residues: MSE    MSE   
Assembly name: RecQ-mediated genome instability protein 1 and RecQ-mediated genome instability protein 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-188447 (Preferred)   search this ID
PDBe-KB: Q9H9A7    Q96E14   
X-ray diffraction
2Å resolution
Released: 22 Sep 2010
Model geometry
Fit model/data
3nbh
3nbh
3nbh
Crystal structure of the human topoisomerase III alpha-RMI1 complex with bound calcium ion
Bocquet N, Bunker RD, Thoma NH
Nat Struct Mol Biol (2014) [PMID: 24509834  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: CA    CA   
Assembly name: DNA topoisomerase 3-alpha and RecQ-mediated genome instability protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-171706 (Preferred)   search this ID
PDBe-KB: Q9H9A7    Q13472   
X-ray diffraction
3.25Å resolution
Released: 12 Feb 2014
Model geometry
Fit model/data
4cht
4cht
4cht
Crystal structure of the RMI core complex with MM2 peptide from FANCM
Hoadley KA, Keck JL
Proc Natl Acad Sci U S A (2012) [PMID: 22392978  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
PDBe complex ID: PDB-CPX-184939 (Preferred)   search this ID
PDBe-KB: Q9H9A7    Q8IYD8    Q96E14   
X-ray diffraction
3.3Å resolution
Released: 14 Mar 2012
Model geometry
Fit model/data
4day
4day
4day
Crystal structure of the human topoisomerase III alpha-RMI1 complex
Bocquet N, Bunker RD, Thoma NH
Nat Struct Mol Biol (2014) [PMID: 24509834  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: MG    MG   
Assembly name: DNA topoisomerase 3-alpha and RecQ-mediated genome instability protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-171706 (Preferred)   search this ID
PDBe-KB: Q9H9A7    Q13472   
X-ray diffraction
2.85Å resolution
Released: 12 Feb 2014
Model geometry
Fit model/data
4cgy
4cgy
4cgy
Crystal structure of human RMI1 N-terminus
Wang F, Yang Y, Singh TR, Busygina V, Guo R, Wan K, Wang W, Sung P, Meetei AR, Lei M
Structure (2010) [PMID: 20826342  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Modified residues: MSE    MSE   
Assembly name: RecQ-mediated genome instability protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-190697 (Preferred)   search this ID
PDBe-KB: Q9H9A7   
X-ray diffraction
2Å resolution
Released: 22 Sep 2010
Model geometry
Fit model/data
3nbi
3nbi
3nbi
Crystal structure of the RMI core complex
Hoadley KA, Xu D, Xue Y, Satyshur KA, Wang W, Keck JL
Structure (2010) [PMID: 20826341  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: BEN   
Assembly name: RecQ-mediated genome instability protein 1 and RecQ-mediated genome instability protein 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-188447 (Preferred)   search this ID
PDBe-KB: Q9H9A7    Q96E14   
X-ray diffraction
1.55Å resolution
Released: 15 Sep 2010
Model geometry
Fit model/data
3mxn
3mxn
3mxn
Entries 1 to 7 of 7
Entries 1 to 7 of 7