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Entry Information
Entry status
(1)
Experimental methods
(1)
Electron Microscopy
(58)
Authors
(141)
Amunts A
(17)
Beckmann R
(15)
Cheng J
(15)
Aibara S
(12)
Singh V
(12)
Berninghausen O
(9)
Li X
(8)
Bohnsack KE
(7)
Hanitsch E
(7)
Hillen HS
(7)
Itoh Y
(7)
Lavdovskaia E
(7)
Linden A
(7)
Modelska A
(7)
Nadler F
(7)
Richter-Dennerlein R
(7)
Urlaub H
(7)
Barrientos A
(6)
Buschauer R
(6)
Denk T
(6)
Li Y
(6)
Minczuk M
(6)
Ramakrishnan V
(6)
Rorbach J
(6)
Wang M
(6)
Andrell J
(5)
Andréll J
(5)
Ban N
(5)
Filipovska A
(5)
Lee RG
(5)
Leibundgut M
(5)
Lenarcic T
(5)
Lenarčič T
(5)
Rackham O
(5)
Saurer M
(5)
Scaiola A
(5)
Schoenhut T
(5)
Schonhut T
(5)
Schönhut T
(5)
Agrawal RK
(4)
Kummer E
(4)
Sharma MR
(4)
Atanassov I
(3)
Bai XC
(3)
Brown A
(3)
Chandrasekaran V
(3)
Cipullo M
(3)
Del'Olio S
(3)
Desai N
(3)
Flygaard RK
(3)
Hassan A
(3)
Izumikawa K
(3)
Jaskolowski M
(3)
Naschberger A
(3)
Nguyen MD
(3)
Nobe Y
(3)
Taoka M
(3)
Whitford PC
(3)
Yang H
(3)
Abdelbagi A
(2)
Andrews B
(2)
Battersby BJ
(2)
Benhalevy D
(2)
Best RB
(2)
Cai Y
(2)
Choi A
(2)
Dent KC
(2)
Dinan A
(2)
Dreos R
(2)
Firth AE
(2)
Garone C
(2)
Gatfield D
(2)
Gopalakrishna S
(2)
Hafner M
(2)
Hallberg BM
(2)
Hällberg BM
(2)
Kazi R
(2)
Keshavan P
(2)
Khawaja A
(2)
Kimanius D
(2)
Koripella RK
(2)
Krueger A
(2)
Liu Y
(2)
Lobo V
(2)
Maiti P
(2)
Marks J
(2)
Miller-Fleming L
(2)
Misic J
(2)
Nadimpalli HP
(2)
Nguyen TG
(2)
Palenikova P
(2)
Pellegrino S
(2)
Pirozhkova MA
(2)
Páleníková P
(2)
Rathore S
(2)
Rebelo-Guiomar P
(2)
Richter U
(2)
Risteff P
(2)
Ritter C
(2)
Rogan JF
(2)
More...
Homo / hetero assembly
(1)
hetero
(58)
Assembly composition
(1)
RNA/protein complex
(58)
Assembly polymer count
(24)
94-mer
(6)
55-mer
(5)
56-mer
(5)
52-mer
(4)
57-mer
(4)
58-mer
(4)
83-mer
(3)
92-mer
(3)
93-mer
(3)
51-mer
(2)
53-mer
(2)
54-mer
(2)
60-mer
(2)
86-mer
(2)
91-mer
(2)
30-mer
(1)
46-mer
(1)
49-mer
(1)
62-mer
(1)
85-mer
(1)
90-mer
(1)
96-mer
(1)
icosamer
(1)
octadecamer
(1)
Resolution distribution
2.0 - 2.5
(5)
2.5 - 3
(17)
3.0 - 3.5
(22)
3.5 - 4
(6)
4.0 - 4.5
(4)
4.5 - 5
(1)
5.5 - 6
(1)
12.0 - 12.5
(1)
14.0 - 14.5
(1)
Release year distribution
2005 - 2010
(2)
2010 - 2015
(1)
2015 - 2020
(12)
2020 - 2025
(51)
2025 - 2030
(1)
Journal
(8)
Nat Commun
(34)
Elife
(8)
Science
(7)
Nat Struct Mol Biol
(3)
Proc Natl Acad Sci U S A
(3)
J Mol Biol
(1)
Nature
(1)
To be published
(1)
Macromolecules
Organism superkingdom
(1)
Eukaryota
(58)
Organism name
(2)
Homo sapiens
(57)
Bos taurus
(1)
Molecule name
(7)
39S ribosomal protein L22, mitochondrial
(58)
L22mt
(58)
Large ribosomal subunit protein uL22m
(58)
MRP-L22
(58)
39S ribosomal protein L25, mitochondrial
(56)
L25mt
(56)
MRP-L25
(56)
Molecule type
(1)
Protein
(58)
Gene names
(4)
MRPL22
(58)
HSPC158
(56)
MRPL25
(56)
RPML25
(56)
Interacting Molecules
(159)
Large ribosomal subunit protein bL17m
(58)
Large ribosomal subunit protein bL27m
(58)
Large ribosomal subunit protein uL16m
(58)
Large ribosomal subunit protein uL24m
(58)
Large ribosomal subunit protein uL2m
(58)
Large ribosomal subunit protein uL4m
(58)
Large ribosomal subunit protein bL19m
(57)
Large ribosomal subunit protein bL20m
(57)
Large ribosomal subunit protein bL33m
(57)
Large ribosomal subunit protein bL34m
(57)
Large ribosomal subunit protein uL13m
(57)
Large ribosomal subunit protein uL3m
(57)
Large ribosomal subunit protein bL21m
(56)
Large ribosomal subunit protein bL28m
(56)
Large ribosomal subunit protein bL32m
(56)
Large ribosomal subunit protein bL9m
(56)
Large ribosomal subunit protein mL37
(56)
Large ribosomal subunit protein mL38
(56)
Large ribosomal subunit protein uL11m
(56)
Large ribosomal subunit protein uL14m
(56)
Large ribosomal subunit protein uL15m
(56)
Large ribosomal subunit protein uL18m
(56)
Large ribosomal subunit protein uL23m
(56)
Large ribosomal subunit protein uL29m
(56)
Large ribosomal subunit protein uL30m
(56)
Large ribosomal subunit protein bL35m
(55)
Large ribosomal subunit protein mL39
(55)
Large ribosomal subunit protein mL41
(55)
Large ribosomal subunit protein mL42
(55)
Large ribosomal subunit protein mL43
(55)
Large ribosomal subunit protein mL44
(55)
Large ribosomal subunit protein mL45
(55)
Large ribosomal subunit protein mL49
(55)
Large ribosomal subunit protein mL50
(55)
Large ribosomal subunit protein mL51
(55)
Large ribosomal subunit protein mL52
(55)
Large ribosomal subunit protein mL62
(55)
Large ribosomal subunit protein mL63
(55)
Large ribosomal subunit protein mL64
(55)
Large ribosomal subunit protein mL65
(55)
Large ribosomal subunit protein mL66
(55)
Large ribosomal subunit protein uL10m
(54)
Large ribosomal subunit protein mL48
(53)
Large ribosomal subunit protein mL53
(53)
Large ribosomal subunit protein mL40
(52)
Large ribosomal subunit protein mL46
(52)
Large ribosomal subunit protein mL55
(51)
Large ribosomal subunit protein mL54
(48)
Large ribosomal subunit protein bL36m
(44)
16S ribosomal RNA
(37)
mitochondrial tRNAVal
(27)
Acyl carrier protein, mitochondrial
(25)
Mitochondrial assembly of ribosomal large subunit protein 1
(25)
Mitochondrial ribosome and complex I assembly factor AltMIEF1
(25)
Small ribosomal subunit protein bS16m
(22)
Small ribosomal subunit protein bS18m
(22)
Small ribosomal subunit protein bS1m
(22)
Small ribosomal subunit protein bS6m
(22)
Small ribosomal subunit protein mS22
(22)
Small ribosomal subunit protein mS23
(22)
Small ribosomal subunit protein mS25
(22)
Small ribosomal subunit protein mS26
(22)
Small ribosomal subunit protein mS27
(22)
Small ribosomal subunit protein mS29
(22)
Small ribosomal subunit protein mS31
(22)
Small ribosomal subunit protein mS33
(22)
Small ribosomal subunit protein mS35
(22)
Small ribosomal subunit protein mS37
(22)
Small ribosomal subunit protein mS38
(22)
Small ribosomal subunit protein mS39
(22)
Small ribosomal subunit protein mS40
(22)
Small ribosomal subunit protein uS10m
(22)
Small ribosomal subunit protein uS11m
(22)
Small ribosomal subunit protein uS12m
(22)
Small ribosomal subunit protein uS14m
(22)
Small ribosomal subunit protein uS15m
(22)
Small ribosomal subunit protein uS17m
(22)
Small ribosomal subunit protein uS2m
(22)
Small ribosomal subunit protein uS3m
(22)
Small ribosomal subunit protein uS5m
(22)
Small ribosomal subunit protein uS7m
(22)
Small ribosomal subunit protein uS9m
(22)
Small ribosomal subunit protein mS34
(21)
Small ribosomal subunit protein bS21m
(19)
Large ribosomal subunit protein bL12m
(16)
16S mitochondrial rRNA
(15)
Messenger RNA
(15)
12S mitochondrial rRNA
(14)
5-cytosine rRNA methyltransferase NSUN4
(11)
Transcription termination factor 4, mitochondrial
(11)
mitochondrial Val tRNA
(9)
Large ribosomal subunit protein uL1m
(8)
E-site tRNA
(7)
12S rRNA
(6)
P-site tRNA
(6)
Val tRNA
(6)
Quinupristin
(5)
mt-tRNAVal
(5)
E/E-tRNA
(4)
P/P-tRNA
(4)
More...
Interacting ligands
(2)
MG : MAGNESIUM ION
(6)
PUT : 1,4-DIAMINOBUTANE
(3)
Function and Biology
Biological function
(2)
structural constituent of ribosome
(57)
RNA binding
(46)
Biological process
(2)
translation
(57)
mitochondrial translation
(46)
Biological cell component
(6)
large ribosomal subunit
(57)
ribosome
(57)
mitochondrial inner membrane
(46)
mitochondrial large ribosomal subunit
(46)
mitochondrion
(46)
ribonucleoprotein complex
(46)
Sequence and Structure classification
CATH class
(1)
Alpha Beta
(3)
CATH topology
(1)
Ribosomal Protein L22; Chain A
(3)
Pfam accession / name
(1)
PF00237 : Ribosomal_L22
(58)
Experimental Information
Diffraction protocol
(1)
Single wavelength
(1)
Refinement software
(4)
PHENIX
(10)
phenix.real_space_refine
(8)
REFMAC
(1)
YAMMP
(1)
EM microscope model
(3)
FEI TITAN KRIOS
(52)
TFS KRIOS
(4)
FEI TECNAI F20
(2)
EM detector name
(7)
GATAN K2 SUMMIT (4k x 4k)
(16)
FEI FALCON II (4k x 4k)
(12)
GATAN K3 (6k x 4k)
(9)
GATAN K3 BIOQUANTUM (6k x 4k)
(9)
FEI FALCON III (4k x 4k)
(8)
FEI FALCON IV (4k x 4k)
(2)
KODAK SO-163 FILM
(1)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
...
Entries 1 to 10 of 58
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Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA
Brown A, Rathore S, Kimanius D, Aibara S, Bai XC, Rorbach J, Amunts A, Ramakrishnan V
Nat Struct Mol Biol
(2017)
[PMID: 28892042 ]
Source organism: Homo sapiens
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-289299 (Preferred)
search this ID
Leishmania Tarentolae Mitochondrial Large Ribosomal Subunit Model
Sharma MR, Booth TM, Simpson L, Maslov DA, Agrawal RK
Proc Natl Acad Sci U S A
(2009)
[PMID: 19497863 ]
Assembly composition: RNA/protein complex
Assembly name:
Large ribosomal protein
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-289428 (Preferred)
search this ID
Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA
Brown A, Rathore S, Kimanius D, Aibara S, Bai XC, Rorbach J, Amunts A, Ramakrishnan V
Nat Struct Mol Biol
(2017)
[PMID: 28892042 ]
Source organism: Homo sapiens
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-289300 (Preferred)
search this ID
Structure of the large ribosomal subunit from human mitochondria
Brown A, Amunts A, Bai XC, Sugimoto Y, Edwards PC, Murshudov G, Scheres SHW, Ramakrishnan V
Science
(2014)
[PMID: 25278503 ]
Source organism: Homo sapiens
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-289429 (Preferred)
search this ID
Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA
Aibara S, Singh V, Modelska A, Amunts A
Elife
(2020)
[PMID: 32812867 ]
Source organism: Homo sapiens
Assembly composition: RNA/protein complex
Assembly name:
ribosomal protein and RNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-127375 (Preferred)
search this ID
Human mitochondrial ribosome in complex with mRNA, P-site tRNA and E-site tRNA
Aibara S, Singh V, Modelska A, Amunts A
Elife
(2020)
[PMID: 32812867 ]
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-240766 (Preferred)
search this ID
Human mitochondrial ribosome in complex with mRNA and P-site tRNA
Aibara S, Singh V, Modelska A, Amunts A
Elife
(2020)
[PMID: 32812867 ]
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-240764 (Preferred)
search this ID
human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7
Kummer E, Nguyen TG, Ritter C
Nat Commun
(2023)
[PMID: 38042949 ]
Source organism: Homo sapiens
Assembly composition: RNA/protein complex
Assembly name:
MTERF4-NSUN4 mitochondiral ribosomal assembly complex and RNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-236432 (Preferred)
search this ID
Human mitochondrial ribosome in complex with antibiotic tigecycline
Khawaja A, Sing V, Nguyen MD, Rorbach J
To be published
Source organism: Homo sapiens
Assembly composition: RNA/protein complex
Modified residues:
OMG
5MC
OMU
5F0
ACE
5MC
ACE
2MG
5MU
5MU
MA6
1MA
THC
1MA
2MG
B8T
PSU
PSU
MA6
OMG
OMU
THC
Assembly name:
ribosomal protein and RNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-290535 (Preferred)
search this ID
39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA
Saurer M, Leibundgut M, Scaiola A, Schoenhut T, Ban N
Science
(2023)
[PMID: 37141370 ]
Source organism: Homo sapiens
Assembly composition: RNA/protein complex
PDBe complex ID:
PDB-CPX-218035 (Preferred)
search this ID
...
Entries 1 to 10 of 58