Filter by :
Entry Information
Entry status
(1)
Experimental methods
(2)
Solution NMR
(4)
Electron Microscopy
(3)
Authors
(56)
Campiglia P
(3)
D'Ursi AM
(3)
Esposito C
(3)
Gomez-Monterrey I
(3)
Novellino E
(3)
Scrima M
(3)
Baneres JL
(2)
Damian M
(2)
Banères JL
(1)
Cai Y
(1)
Cantel S
(1)
Czaplicki G
(1)
Delort B
(1)
Demange P
(1)
Fehrentz JA
(1)
Ferre G
(1)
Ferré G
(1)
Floquet N
(1)
Gavara L
(1)
Guo J
(1)
Guo S
(1)
He X
(1)
Hirata K
(1)
Ji S
(1)
Ji SY
(1)
Jiang Y
(1)
Liu H
(1)
Louet M
(1)
M'Kadmi C
(1)
Ma Y
(1)
Mao C
(1)
Marie J
(1)
Milon A
(1)
Ming Q
(1)
Myasnikov A
(1)
Qin J
(1)
Renault P
(1)
Saurel O
(1)
Shao Z
(1)
Shen D
(1)
Shen DD
(1)
Sun D
(1)
Sun J
(1)
Wang Y
(1)
Wu C
(1)
Xie X
(1)
Xu HE
(1)
Xu P
(1)
Xu Z
(1)
Yan W
(1)
Yin W
(1)
Yun Y
(1)
Zhang C
(1)
Zhang H
(1)
Zhang Y
(1)
Zhuang Y
(1)
Homo / hetero assembly
(2)
homo
(4)
hetero
(3)
Assembly composition
(2)
protein structure
(4)
protein/protein complex
(3)
Assembly polymer count
(2)
monomer
(4)
hexamer
(3)
Resolution distribution
2.5 - 3
(3)
Release year distribution
2005 - 2010
(3)
2015 - 2020
(1)
2020 - 2025
(3)
Journal
(3)
Biochem Biophys Res Commun
(3)
Nat Commun
(3)
Proc Natl Acad Sci U S A
(1)
Macromolecules
Organism superkingdom
(1)
Eukaryota
(7)
Organism name
(2)
Homo sapiens
(4)
Mus musculus
(3)
Molecule name
(9)
Appetite-regulating hormone
(7)
Ghrelin
(7)
Growth hormone secretagogue
(7)
Growth hormone-releasing peptide
(7)
Motilin-related peptide
(7)
Obestatin
(7)
Protein M46
(7)
Ghrelin-27
(4)
Ghrelin-28
(4)
Molecule type
(1)
Protein
(7)
Gene names
(5)
GHRL
(4)
MTLRP
(4)
UNQ524/PRO1066
(4)
Ghrl
(3)
Mtlrp
(3)
Interacting Molecules
(10)
Growth hormone secretagogue receptor type 1
(3)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
(3)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
(3)
Antibody fragment
(1)
Engineered G-alpha-q subunit
(1)
Guanine nucleotide-binding protein G(i) subunit alpha-1
(1)
Guanine nucleotide-binding protein G(o) subunit alpha
(1)
NB35
(1)
ScFv16
(1)
Soluble cytochrome b562
(1)
Interacting ligands
(2)
FKZ : octan-1-amine
(1)
OCA : OCTANOIC ACID (CAPRYLIC ACID)
(1)
Function and Biology
Biological function
(2)
hormone activity
(5)
growth hormone-releasing hormone activity
(1)
Biological cell component
(1)
extracellular region
(5)
Sequence and Structure classification
Pfam accession / name
(2)
PF04644 : Motilin_ghrelin
(4)
PF04643 : Motilin_assoc
(2)
Experimental Information
Refinement software
(1)
PHENIX
(1)
EM microscope model
(1)
FEI TITAN KRIOS
(3)
EM detector name
(2)
GATAN K3 (6k x 4k)
(2)
GATAN K2 SUMMIT (4k x 4k)
(1)
NMR
NMR software packages
(4)
DYANA
(3)
Amber
(1)
Sparky
(1)
TopSpin
(1)
NMR Field Strength
500.0 - 600
(3)
600.0 - 700
(4)
700.0 - 800
(1)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
Entries 1 to 7 of 7
Select all entries on this page
Receptor-bound Ghrelin conformation
Ferre G, Damian M, M'Kadmi C, Saurel O, Czaplicki G, Demange P, Marie J, Fehrentz JA, Baneres JL, Milon A
Proc Natl Acad Sci U S A
(2019)
[PMID: 31416915 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Bound ligands:
FKZ
Assembly name:
Ghrelin-27
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-193676 (Preferred)
search this ID

Cryo-EM structure of the ghrelin-bound human ghrelin receptor-Go complex
Qin J, Ming Q, Ji S, Mao C, Shen D, Zhang Y
Nat Commun
(2022)
[PMID: 35027551 ]
Source organisms: synthetic construct , Homo sapiens
Assembly composition: protein/protein complex
Modified residues:
K4Q
PDBe complex ID:
PDB-CPX-209412 (Preferred)
search this ID
Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist
Liu H, Sun D, Sun J, Zhang C
Nat Commun
(2021)
Source organisms: Mus musculus , Homo sapiens
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-211371 (Preferred)
search this ID
ghrelin-bound ghrelin receptor in complex with Gq
Wang Y, Zhuang Y, Xu P, Xu HE, Jiang Y
Nat Commun
(2021)
[PMID: 34417468 ]
Source organisms: Lama glama , Homo sapiens
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-209564 (Preferred)
search this ID
11-23 obestatin fragment in DPC/SDS micellar solution
D'Ursi AM, Scrima M, Esposito C, Campiglia P
Biochem Biophys Res Commun
(2007)
[PMID: 17904104 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Obestatin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-190165 (Preferred)
search this ID

Obestatin in water solution
D'Ursi AM, Scrima M, Esposito C, Campiglia P
Biochem Biophys Res Commun
(2007)
[PMID: 17904104 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Obestatin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-190165 (Preferred)
search this ID

obestatin NMR structure in SDS/DPC micellar solution
D'Ursi AM, Scrima M, Esposito C, Campiglia P
Biochem Biophys Res Commun
(2007)
[PMID: 17904104 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Obestatin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-190165 (Preferred)
search this ID

Entries 1 to 7 of 7