PDBsum entry 3sgo

Protein fibril

PDB id: 3sgo

Contents

Protein chain

11 a.a.

Waters ×1

PDB id:

3sgo

Name:

Protein fibril

Title:

Amyloid-related segment of alphab-crystallin residues 90-100

Structure:

Alpha-crystallin b chain. Chain: a. Synonym: alpha(b)-crystallin, heat shock protein beta-5, hspb5, renal carcinoma antigen ny-ren-27, rosenthal fiber component. Engineered: yes

Source:

Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: synthetic peptide

Resolution:

2.56Å R-factor: 0.245 R-free: 0.270

Authors:

A.Laganowsky,M.R.Sawaya,D.Cascio,D.Eisenberg

Key ref:

A.Laganowsky et al. (2012). Atomic view of a toxic amyloid small oligomer. Science, 335, 1228-1231. PubMed id: 22403391

Date:

15-Jun-11 Release date: 21-Mar-12

Protein chain

P02511  (CRYAB_HUMAN) -  Alpha-crystallin B chain from Homo sapiens

Seq: 175 a.a.

Struc: 11 a.a.

Enzyme reactions

• Enzyme class: E.C.?

Science 335:1228-1231 (2012)

PubMed id: 22403391

Atomic view of a toxic amyloid small oligomer.

A.Laganowsky, C.Liu, M.R.Sawaya, J.P.Whitelegge, J.Park, M.Zhao, A.Pensalfini, A.B.Soriaga, M.Landau, P.K.Teng, D.Cascio, C.Glabe, D.Eisenberg.

ABSTRACT

No abstract given.