Crystal structure of t6 fab bound to thesars-cov-2 rbd of b.1.351
Structure:
T6 light chain. Chain: l, a. Engineered: yes. Spike protein s1. Chain: e, b. Fragment: receptor binding domain. Engineered: yes. T6 heavy chain. Chain: h, c.
Source:
Homo sapiens. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: s, 2. Expression_system_taxid: 9606
Resolution:
2.90Å
R-factor:
0.220
R-free:
0.285
Authors:
X.Wang,L.Zhang,S.Zhang,Q.Liang
Key ref:
Q.Liang
et al.
(2022).
Rbd trimer mRNA vaccine elicits broad and protective responses against sars-Cov-2 variants..
Iscience,
25,
04043.
PubMed id: 35291264
Date:
04-Aug-21
Release date:
27-Apr-22
PROCHECK
Headers
References
Protein chains
No UniProt id for this chain
Struc:
219 a.a.
Protein chains
P0DTC2 (SPIKE_SARS2) -
Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2
Seq: Struc:
 
Seq: Struc:
 
Seq: Struc:
1273 a.a.
192 a.a.*
Protein chains
No UniProt id for this chain
Struc:
216 a.a.
Key:
PfamA domain
Secondary structure
*
PDB and UniProt seqs differ
at 3 residue positions (black
crosses)