Training

UniProt provides the scientific community with a comprehensive, highly-quality, and freely accessible resource of protein sequence and functional information. This seminar will explain how UniProt annotate and cross-reference data from around the globe; show what kinds of information are available in UniProt, how to access it, how to search the database and make use of the tools available.

Audience

This seminar is open to all faculty, staff, and students. An undergraduate degree in a life science subject, and some background in the molecular structure of proteins would be an advantage. Participants should be confident in the use of PCs and Internet browsing, no previous knowledge of bioinformatics is required.

Modules and Resources

During this course you will learn about:

• Protein sequence databases

UniProt

• Introduction
• Two sides of UniProtKB: TrEMBL & SwissProt
• Contents of a SwissProt entry
• Proteomes
• Automatic annotation
• Cross-references
• Searching UniProt
• Alignments
• Accessing UniProt Programmatically

Learning Objectives

After this course you should be able to:

• Understand the curation mechanics behind UniProt
• Browse the UniProt database in detail, learning about its structure and the type of data it contains
• Select the most appropriate way to access sequence data for a specific purpose (sequence search, text search...)
• Accessing data programmatically