This term is obsolete.

GO:0000026 JSON

alpha-1,2-mannosyltransferase activity

Molecular Function

Definition (GO:0000026 GONUTS page)

Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage. PMID:10521541

36,198 annotations

Ancestor Chart

Ancestor chart for GO:0000026
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000026

Child Term Relationship to
GO:0000026
dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
is_a
dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
is_a
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
is_a
lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016757 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A6KJI3 10116 A6KJI3_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D6WQD5 7070 D6WQD5_TRICA GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q6AYL7 10116 Q6AYL7_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7JRM5 7227 Q7JRM5_DROME GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
Reactome R-HSA-446187
Reactome R-HSA-446215
Reactome R-HSA-446216
Reactome R-HSA-4551297
Reactome R-HSA-4720478
Reactome R-HSA-9035514

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0000026 based on ALL annotations
The top 100 of 304 co-occurring terms
Co-occurring Term PR S% #Together #Compared
alpha-1,2-mannosyltransferase activity
8,498.88 100.00 22,937 22,937
cell wall mannoprotein biosynthetic process
5,456.61 29.40 8,064 12,560
mannan biosynthetic process
8,236.66 18.52 4,272 4,408
protein mannosylation
7,738.11 18.29 4,272 4,692
dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
7,873.70 11.26 2,607 2,814
dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
7,873.70 11.26 2,607 2,814
mannosyltransferase activity
797.92 8.16 8,801 93,742
protein N-linked glycosylation
520.42 5.82 12,304 200,936
protein glycosylation
414.22 4.76 15,588 319,828
GPI anchor biosynthetic process
352.98 3.75 6,357 153,059
Totals 168138 70806071
No co-occurrence statistics for GO:0000026 based on MANUAL annotations
The top 73 of 73 co-occurring terms
Co-occurring Term PR S% #Together #Compared
alpha-1,2-mannosyltransferase activity
3,680.34 100.00 351 351
mannan biosynthetic process
3,680.34 16.24 57 57
cell wall mannoprotein biosynthetic process
1,952.18 15.06 61 115
protein mannosylation
2,411.26 14.96 57 87
protein N-linked glycosylation
231.18 5.85 162 2,579
GPI anchor biosynthetic process
228.60 5.62 131 2,109
dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
3,680.34 1.99 7 7
dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
3,680.34 1.99 7 7
mannosyltransferase activity
103.41 1.81 17 605
protein O-linked glycosylation
75.01 1.69 32 1,570
Totals 1372 1071606

Change Log

Timestamp Action Category Detail
2019-05-04 Added XREF Reactome:R-HSA-9035514
2019-05-04 Added XREF Reactome:R-HSA-4551297
2019-05-04 Added XREF Reactome:R-HSA-4720478
2019-04-30 Deleted XREF Reactome:R-HSA-4551297
2019-04-30 Deleted XREF Reactome:R-HSA-4720478
2019-04-30 Deleted XREF Reactome:R-HSA-9035514
2019-04-29 Added XREF Reactome:R-HSA-4720478
2019-04-29 Added XREF Reactome:R-HSA-4551297
2019-04-29 Added XREF Reactome:R-HSA-9035514
2019-04-28 Deleted XREF Reactome:R-HSA-9035514
Timestamp Action Category Detail
2003-03-19 Updated TERM alpha-1,2-mannosyltransferase activity
2002-02-06 Updated TERM alpha-1,2-mannosyltransferase
2001-04-03 Updated TERM alpha-1,2-mannosyltransferase
2001-03-30 Added TERM alpha-1,2-mannosyltransferase
Timestamp Action Category Detail
2011-10-29 Added DEFINITION Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.
2011-10-29 Deleted DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-(1->2) linkage.
2011-10-28 Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-(1->2) linkage.
2011-10-28 Deleted DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage.
2008-05-13 Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage.
2004-03-09 Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0000030 (mannosyltransferase activity)
Timestamp Action Category Detail
2019-05-04 Added XREF Reactome:R-HSA-9035514
2019-05-04 Added XREF Reactome:R-HSA-4551297
2019-05-04 Added XREF Reactome:R-HSA-4720478
2019-04-30 Deleted XREF Reactome:R-HSA-4551297
2019-04-30 Deleted XREF Reactome:R-HSA-4720478
2019-04-30 Deleted XREF Reactome:R-HSA-9035514
2019-04-29 Added XREF Reactome:R-HSA-4720478
2019-04-29 Added XREF Reactome:R-HSA-4551297
2019-04-29 Added XREF Reactome:R-HSA-9035514
2019-04-28 Deleted XREF Reactome:R-HSA-9035514
2019-04-28 Deleted XREF Reactome:R-HSA-4551297
2019-04-28 Deleted XREF Reactome:R-HSA-4720478
2019-04-27 Added XREF Reactome:R-HSA-4551297
2019-04-27 Added XREF Reactome:R-HSA-9035514
2019-04-27 Added XREF Reactome:R-HSA-4720478
2019-04-23 Deleted XREF Reactome:R-HSA-4720478
2019-04-23 Deleted XREF Reactome:R-HSA-4551297
2019-04-23 Deleted XREF Reactome:R-HSA-9035514
2019-04-01 Deleted XREF reactome:R-HSA-446216
2019-04-01 Added XREF Reactome:R-HSA-4551297
2019-04-01 Added XREF Reactome:R-HSA-446215
2019-04-01 Added XREF Reactome:R-HSA-446216
2019-04-01 Added XREF Reactome:R-HSA-9035514
2019-04-01 Added XREF Reactome:R-HSA-446187
2019-04-01 Deleted XREF reactome:R-HSA-446215
2019-04-01 Added XREF Reactome:R-HSA-4720478
2019-04-01 Deleted XREF reactome:R-HSA-446187
2018-12-11 Added XREF reactome:R-HSA-446216
2018-12-11 Added XREF reactome:R-HSA-446215
2018-12-11 Added XREF reactome:R-HSA-446187
2017-10-08 Deleted XREF EC:2.4.1
2016-10-03 Deleted XREF EC:2.4.1.-
2016-10-03 Added XREF EC:2.4.1
2001-03-30 Added XREF EC:2.4.1.-
Timestamp Action Category Detail
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