This term is obsolete.

GO:0000105 JSON

L-histidine biosynthetic process

Biological Process

Definition (GO:0000105 GONUTS page)

The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

446,775 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
histidine formation exact
histidine biosynthesis exact
histidine biosynthetic process broad
histidine anabolism exact
histidine synthesis exact

Ancestor Chart

Ancestor chart for GO:0000105
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000105

Child Term Relationship to
GO:0000105
GO:0120213
regulation of histidine biosynthetic process
regulates
GO:0120215
positive regulation of histidine biosynthetic process
positively_regulates
GO:0120214
negative regulation of histidine biosynthetic process
negatively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0000105 L-histidine biosynthetic process Never in Taxon 9606 Homo sapiens

More information on taxon constraints in GO is available here

Cross-references

Database ID Description
InterPro IPR000807 Imidazoleglycerol-phosphate dehydratase
InterPro IPR001348 ATP phosphoribosyltransferase HisG
InterPro IPR002496 Phosphoribosyl-AMP cyclohydrolase domain
InterPro IPR004517 ATP phosphoribosyltransferase regulatory subunit
InterPro IPR004651 Histidine biosynthesis, HisF
InterPro IPR005861 Histidinol-phosphate aminotransferase family
InterPro IPR005954 Histidine biosynthesis bifunctional protein, N-terminal histidinol-phosphatase domain
InterPro IPR006062 Histidine biosynthesis protein
InterPro IPR006063 HisA, bacterial-type
InterPro IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_output CHEBI CHEBI:57595 L-histidine zwitterion

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0009076 obsolete histidine family amino acid biosynthetic process replaced_by GO:0000105

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0000105 based on ALL annotations
The top 100 of 868 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0000105
L-histidine biosynthetic process
444.10 100.00 446,199 446,199
GO:0000107
imidazoleglycerol-phosphate synthase activity
433.81 18.03 80,801 82,717
GO:0004400
histidinol-phosphate transaminase activity
429.15 11.50 51,527 53,322
GO:0004399
histidinol dehydrogenase activity
443.43 10.46 46,688 46,758
GO:0004477
methenyltetrahydrofolate cyclohydrolase activity
332.07 9.80 45,234 60,494
GO:0004488
methylenetetrahydrofolate dehydrogenase (NADP+) activity
316.64 9.74 45,243 63,454
GO:0003949
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
443.28 9.21 41,121 41,197
GO:0003879
ATP phosphoribosyltransferase activity
442.17 8.93 39,879 40,053
GO:0004635
phosphoribosyl-AMP cyclohydrolase activity
443.57 8.77 39,122 39,168
GO:0004424
imidazoleglycerol-phosphate dehydratase activity
443.12 8.69 38,803 38,888
Totals 2662676 184741685
No co-occurrence statistics for GO:0000105 based on MANUAL annotations
The top 51 of 51 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0000105
L-histidine biosynthetic process
2,516.10 100.00 561 561
GO:0003879
ATP phosphoribosyltransferase activity
2,516.10 21.57 121 121
GO:0004424
imidazoleglycerol-phosphate dehydratase activity
2,494.22 20.28 114 115
GO:0003949
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
2,516.10 19.25 108 108
GO:0004399
histidinol dehydrogenase activity
2,493.02 19.22 108 109
GO:0042578
phosphoric ester hydrolase activity
1,974.66 10.73 62 79
GO:0004401
histidinol-phosphatase activity
2,516.10 5.88 33 33
GO:0004400
histidinol-phosphate transaminase activity
2,516.10 0.89 5 5
GO:0004636
phosphoribosyl-ATP diphosphatase activity
2,516.10 0.89 5 5
GO:0004635
phosphoribosyl-AMP cyclohydrolase activity
2,516.10 0.89 5 5
Totals 1467 814906

Change Log

Timestamp Action Category Detail
2025-02-06 Deleted CONSTRAINT in_taxon NCBITaxon:9606 (Homo sapiens)
2025-02-06 Added CONSTRAINT never_in_taxon NCBITaxon:9606 (Homo sapiens)
2025-01-23 Added CONSTRAINT in_taxon NCBITaxon:9606 (Homo sapiens)
2024-05-07 Added DEFINITION The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2024-05-07 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2024-05-07 Updated TERM L-histidine biosynthetic process
2024-05-07 Added RELATION is a GO:0170034 (L-amino acid biosynthetic process)
2024-05-07 Added RELATION is a GO:0170038 (proteinogenic amino acid biosynthetic process)
2024-05-07 Added RELATION is a GO:0009073 (aromatic amino acid family biosynthetic process)
2024-05-07 Deleted RELATION is a GO:1901566 (obsolete organonitrogen compound biosynthetic process)
Timestamp Action Category Detail
2024-05-07 Updated TERM L-histidine biosynthetic process
2007-01-15 Updated TERM histidine biosynthetic process
2002-02-06 Updated TERM histidine biosynthesis
2001-04-03 Updated TERM histidine biosynthesis
2001-03-30 Added TERM histidine biosynthesis
Timestamp Action Category Detail
2024-05-07 Added DEFINITION The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2024-05-07 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2024-05-07 Added SYNONYM histidine biosynthetic process
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2007-08-09 Deleted SYNONYM histidine anabolism
2007-08-09 Deleted SYNONYM histidine formation
2007-08-09 Deleted SYNONYM histidine synthesis
2007-08-09 Added SYNONYM histidine formation
2007-08-09 Added SYNONYM histidine anabolism
2007-08-09 Added SYNONYM histidine biosynthesis
2007-08-09 Added SYNONYM histidine synthesis
2007-08-09 Deleted SYNONYM histidine biosynthesis
2007-01-15 Added SYNONYM histidine biosynthesis
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
2005-08-10 Added SYNONYM histidine formation
2005-08-10 Added SYNONYM histidine synthesis
2005-08-10 Added SYNONYM histidine anabolism
2002-11-27 Added DEFINITION The formation from simpler components of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
Timestamp Action Category Detail
2024-05-07 Added RELATION is a GO:0170034 (L-amino acid biosynthetic process)
2024-05-07 Added RELATION is a GO:0170038 (proteinogenic amino acid biosynthetic process)
2024-05-07 Added RELATION is a GO:0009073 (aromatic amino acid family biosynthetic process)
2024-05-07 Deleted RELATION is a GO:1901566 (obsolete organonitrogen compound biosynthetic process)
2024-05-07 Deleted RELATION is a GO:0046394 (carboxylic acid biosynthetic process)
2024-03-26 Added RELATION is a GO:1901566 (obsolete organonitrogen compound biosynthetic process)
2024-03-26 Deleted RELATION is a GO:0008652 (amino acid biosynthetic process)
2024-03-26 Added RELATION is a GO:0046394 (carboxylic acid biosynthetic process)
2020-11-03 Deleted RELATION is a GO:1901607 (alpha-amino acid biosynthetic process)
2020-11-03 Deleted RELATION is a GO:0009073 (aromatic amino acid family biosynthetic process)
2020-11-03 Deleted RELATION is a GO:0018130 (obsolete heterocycle biosynthetic process)
2020-11-03 Added RELATION is a GO:0008652 (amino acid biosynthetic process)
2018-06-16 Added RELATION is a GO:0009073 (aromatic amino acid family biosynthetic process)
2018-06-16 Deleted RELATION is a GO:0019438 (obsolete aromatic compound biosynthetic process)
2018-06-16 Deleted RELATION is a GO:1901362 (obsolete organic cyclic compound biosynthetic process)
2016-11-28 Added RELATION is a GO:1901607 (alpha-amino acid biosynthetic process)
2016-11-28 Deleted RELATION is a GO:0008652 (amino acid biosynthetic process)
2016-11-28 Added RELATION is a GO:1901362 (obsolete organic cyclic compound biosynthetic process)
2016-11-28 Added RELATION is a GO:0019438 (obsolete aromatic compound biosynthetic process)
2016-11-28 Added RELATION is a GO:0018130 (obsolete heterocycle biosynthetic process)
2016-06-22 Deleted RELATION is a GO:0019438 (obsolete aromatic compound biosynthetic process)
2016-06-22 Added RELATION is a GO:0008652 (amino acid biosynthetic process)
2016-06-22 Deleted RELATION is a GO:1901362 (obsolete organic cyclic compound biosynthetic process)
2016-06-22 Deleted RELATION is a GO:1901607 (alpha-amino acid biosynthetic process)
2016-06-22 Deleted RELATION is a GO:0018130 (obsolete heterocycle biosynthetic process)
2013-06-12 Deleted RELATION is a GO:0009076 (obsolete histidine family amino acid biosynthetic process)
2012-11-10 Added RELATION is a GO:1901607 (alpha-amino acid biosynthetic process)
2012-11-02 Added RELATION is a GO:0019438 (obsolete aromatic compound biosynthetic process)
2012-09-19 Added RELATION is a GO:1901362 (obsolete organic cyclic compound biosynthetic process)
2009-08-31 Added RELATION is a GO:0018130 (obsolete heterocycle biosynthetic process)
2008-04-01 Updated RELATION is a GO:0006547 (L-histidine metabolic process)
2008-04-01 Updated RELATION is a GO:0009076 (obsolete histidine family amino acid biosynthetic process)
Timestamp Action Category Detail
2020-02-28 Deleted XREF MIPS_funcat:01.01.09.07.01
2019-05-04 Added XREF MIPS_funcat:01.01.09.07.01
2003-10-27 Added XREF MetaCyc:HISTSYN-PWY
Timestamp Action Category Detail
2025-02-06 Deleted CONSTRAINT in_taxon NCBITaxon:9606 (Homo sapiens)
2025-02-06 Added CONSTRAINT never_in_taxon NCBITaxon:9606 (Homo sapiens)
2025-01-23 Added CONSTRAINT in_taxon NCBITaxon:9606 (Homo sapiens)
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